Do Neurons die (or are they asleep) ...

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12-11-2008, 02:14 AM

RLSmi

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Join Date: Oct 2006

Location: dx'd4/01@63 Louisiana

Posts: 562

RLSmi

Member

Join Date: Oct 2006

Location: dx'd4/01@63 Louisiana

Posts: 562

I think the main evidence for assuming death of the dopaminergic neurons is the loss of tyrosine hydroxylase-positive cells in PD substantia nigra observed post-mortem, compared to normal post-mortem SN. Also, the progressive loss of dopamine re-uptake as indicated by PET and SPECT data with labeled fluorodopa and beta CIT suggests cell death.

Robert

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