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01-28-2009, 12:41 PM | #1 | |||
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In Remembrance
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More on the role of the BBB in neurological disease.
This one says, " BBB leakage occurs in a variety of neurological disorders like Alzheimer's sickness." Ron http://www.content4reprint.com/healt...in-healthy.htm Drink Coffee to Keep Your Body and Brain Healthy A cup of coffee daily will help you in more tactics than you think. For instance, the daily dose of caffeine can keep Alzheimer's sickness in check, can help reduce cholesterol, protects against dementia, and decreases the chance of developing type 2 diabetes. A daily dose of caffeine blocks the disruptive effects of high cholesterol that scientists link with Alzheimer's illness. Caffeine equivalent of just a daily cup of Joe could protect the blood-brain barrier ( BBB ) from damage that occurs with a fat heavy diet, according to a study. The BBB protects the central nervous system ( CNS ) from what's left of the body's circulation, providing the brain with its own controlled micro-environment. Previous research has demonstrated that raised levels of cholesterol break down the BBB which will then no longer protect the CNS from the damage due to blood borne contamination. BBB leakage occurs in a variety of neurological disorders like Alzheimer's sickness. In one report, researchers of School of North Dakota ( UND ) gave rabbits 3 mg caffeine daily or the equivalent of an average daily cup of joe. The rabbits were fed a cholesterol-enriched diet in this time. After 12 weeks some lab tests indicated the BBB was noticeably more intact in rabbits getting a daily dose of caffeine. The findings of the study have been broadcast in the open access Book of Neuroinflammation. "Caffeine appears to block many of the disruptive results of cholesterol that make the blood-brain barrier leaky," says Jonathan Geige of UND. "High levels of cholesterol are a risk factor for Alzheimer's sickness, perhaps by compromising the defending nature of the blood-brain barrier. For the first time we've shown that chronic ingestion of caffeine protects the BBB from cholesterol-induced leakage. Caffeine is a safe and generally available drug and its capacity to stabilise the blood-brain barrier means it could have a critical part to play in therapies against neurological disorders." Danish and Swedish researchers have disclosed that folks who drank three to five cups of coffee daily were 60 5 % not as sure to have developed dementia, compared to people who drank 2 cups or less. Earlier studies have linked coffee to a number of health perks that will make a contribution to this latest finding.
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