Parkinson's Disease Tulip


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Old 02-24-2009, 05:26 AM #1
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Default Methylene Blue

Has anyone tried Methylene Blue?

I've seen it mentioned here before,
http://neurotalk.psychcentral.com/sh...Methylene+Blue
http://neurotalk.psychcentral.com/sh...Methylene+Blue

Just curious. Couldn't sleep so I decided to read about fungus and antifungal foods when I came across rember, a drug from http://www.taurx.com mentioning that it "may" slow the progression.

... and since it's 3 AM and I'm a bit silly, I came up with a new word:

inflamection - ĭn-flam-ĕk'shən
n.
    1. Invasion by and multiplication of pathogenic microorganisms in a bodily part or tissue, resulting in a "suspected" protective reaction of tissue to irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes loss of function.
    1. Moral contamination or corruption resulting in double talk and denial.

Use it in a sentence
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girija (02-24-2009)

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Old 02-24-2009, 06:41 AM #2
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Default Some links

I haven't tried it, although it is on The List. As has been pointed out, it is not going to be a big money maker if it works. So, we would probably be seeing a low level of interest whether it worked or not. So, that leaves the freelancers-
http://www.earthclinic.com/CURES/parkinsons.html
http://www.eurekalert.org/pub_releas...-cho081508.php
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 02-24-2009, 06:52 AM #3
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Default A little more

While not specifically about methylene blue, the EurekaAlert above quoted Dr. Bruce Ames praising the work. Ames is a pretty heavy fellow as noted in this NIH blurb:
"Dr. Ames was director of the National Institute of Environmental Health Sciences Center at U.C. Berkeley for twenty-three years, and he chaired the U.C. Berkeley Department of Biochemistry for six years, 1983–1989. Prior to that he was the Microbial Genetics section chief at the National Institutes of Health in Bethesda, Maryland, a National Science Foundation senior fellow in the laboratories of Frances Crick in Cambridge, England, and F. Jacob in Paris, France, and a biochemist with the National Institutes of Health, where he began his career."
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 02-24-2009, 07:27 AM #4
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Default duodopa trial design

I read on another forum that the duodopa trial is set to last one year, during which the participants will be off their oral meds, and after which, they will no longer be able to get their levodopa/carbi through the tube, but will have to go back onto their oral med regime.

If true, who in the world would be willing to sign up for this? Please tell me this is not correct. And if correct, whoever designed this trial has no clue. Would THEY (the trial designers) be willing to go off their oral meds for one year, only to have to titrate all the way back up to where they were, or now needed to be because of the year gone by? And what about that tube? Do they take it back out, again another surgery? And what about the emotional impact of perhaps feeling better than you have in years, only to have that taken away (deja vue GDNF...)

If true, good luck with this trial. Perhaps it is not too late for them to reconsider the design?
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Old 02-24-2009, 08:41 AM #5
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Default

Quote:
Originally Posted by lurkingforacure View Post
I read on another forum that the duodopa trial is set to last one year, during which the participants will be off their oral meds, and after which, they will no longer be able to get their levodopa/carbi through the tube, but will have to go back onto their oral med regime.

I think Duodopa is used when traditional oral medications don't effectively manage the symptoms of PD.

http://www.duodopa.com/faqs/faqsabou...0-2-0,00.htm#2
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Old 02-24-2009, 11:13 AM #6
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Default

[*] Moral contamination or corruption resulting in double talk and deniall

Use it in a sentence [/QUOTE]

Very nice definition, tempted to use it in many sentences, but dont want to bring politics here!!

thanks!
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Old 02-25-2009, 04:46 PM #7
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Default just reading this

Robert,

i like it! inflamection - i'd put it right up there with clognition. In fact, inflamections could cause clognition. That's a sentence. Here's a question:

Will congress ever find a cure for its' advanced inflamection?

paula
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