Parkinson's Disease Tulip


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Old 05-11-2009, 10:48 AM #1
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Fish clue to Parkinson's treatment

Published Date: 09 May 2009, By John Roberts, Education Correspondent
http://www.yorkshirepost.co.uk/news/...ent.5251197.jp

SCIENTISTS in Yorkshire have been given almost a quarter of a million pounds to find ways of slowing down the onset of Parkinson's disease. Sheffield University will be given the funding by the Parkinson's Disease Society to focus on an inherited form of the condition which can strike people at an early age. Researchers believe that the most common cause for early onset of the condition is a mutation in a gene known as PARK2.


Protein Might Mute Effects of Methamphetamine

05.08.09, 04:00 PM EDT
http://www.forbes.com/feeds/hscout/2...out626856.html

Manipulation may be used someday against Parkinson's, too, expert suggests

FRIDAY, May 8 (HealthDay News) -- A protein that appears to lend a hand in the death of brain cells tied to Parkinson's disease might also help fight drug addiction, according to a newly published study. The protein -- organic cation transporter 3, or oct3 -- normally guides molecules in and out of cells, but it seems to lead the toxic brain chemical MPP+ straight to brain cells, where it kills dopamine neurons, which play a key role in helping people move, the study found in a study in mice.


CPT confirms its commitment to the development of Cogane for the treatment of Parkinson's Disease

CPT commits to hosting a Key Opinion Leader Event to expediate the development of Cogane

http://www.pharmalive.com/News/Index...ticleid=623955

GODMANCHESTER, Cambridgeshire, U.K. (05 May 2009) – Phytopharm plc (LSE: PYM) (“Phytopharm” or the “Company”) announces today that The Cure Parkinson's Trust (CPT) has commited to supporting the development of Cogane™ as a treatment for Parkinson’s disease (PD). The CPT will host an International Key Opinion Leader Event on 11-12 May 2009 in order to facilitate the progression of Cogane™.


Good to the last drop
New research suggests drinking coffee might actually be good for you

By Judy Foreman The Boston Globe, May 11, 2009
http://www.boston.com/news/health/ar...the_last_drop/

The heavenly brew, once deemed harmful to health, is turning out to be, if not quite a health food, at least a low-risk drink, and in many ways a beneficial one. It could protect against diabetes, liver cancer, cirrhosis, and Parkinson's disease. What happened? New research - lots of it - and the recognition that older, negative studies often failed to tease apart the effects of coffee and those of smoking because so many coffee drinkers were also smokers. "Coffee was seen as very unhealthy," said Rob van Dam, a coffee researcher and epidemiologist at the Harvard School of Public Health. "Now we have a more balanced view. We're not telling people to drink it for health. But it is a good beverage choice."


University awarded Parkinson's funding

The Sheffield Telegraph (UK), Published Date: 11 May 2009
http://www.sheffieldtelegraph.co.uk/...ing.5252643.jp

The Parkinson's Disease Society (PDS) has announced funding of nearly £240,000 towards research at the University of Sheffield which will look into the possibility of slowing down the onset of Parkinson's disease. Dr Oliver Bandmann and his team at the University will focus on the gene PARK 2, as this is associated with an inherited form of Parkinson's disease that strikes at an early age, but can also result in Parkinson's disease presenting later in life It is estimated that 1 in 20 people with Parkinson's are under the age of 40 when diagnosed. Dr Bandmann's team will use tropical zebrafish, which are around 3cm long for the study, because their PARK 2 gene is very similar to that found in humans.


Are Short Drug Patents Hurting Patients?

Matthew Herper, 05.11.09, 08:40 AM EDT
http://www.forbes.com/2009/05/10/pha...ess_healthcare

Developing drugs takes longer than ever, but patent laws don't recognize that. But, because of a legal snafu, we'll never know if Angiomax can help in all of these conditions: In 2001, lawyers representing the drug maker missed--by one day--filing for an automatic extension of the patent on the drug to make up for time lost to regulatory delays. That shortened Angiomax's patent life by five years, making it unlikely the Medicines Company (MDCO - news - people) would ever make back its money if it funded the relevant studies. "If we had the correct incentive, we would not only have started these trials, some of them would have been completed," says Clive Meanwell, the company's chief executive.


Neurological Diseases Major Discovery

Medical News Today, Article Date: 09 May 2009 - 0:00 PDT
http://www.medicalnewstoday.com/articles/149384.php

In many neurodegenerative diseases, a main factor that kills neurons is excessive levels of glutamate, the most abundant excitatory neurotransmitter in many regions of the central nervous system (CNS). Diseases that occur as a result of high glutamate levels include hypoxic-ischemic brain injury (stroke), trauma, seizures, various forms of dementia and neurodegeneration. For years, the main explanation for the toxic effects of glutamate is that it overexcites neuronal cells via activation of glutamate receptors and thereby kills them.

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