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10-26-2009, 03:36 PM | #1 | |||
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Wisest Elder Ever
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Sprue is celiac, and/or gluten intolerance.
Sjorgrens is an autoimmune disease more common in women, but may rarely occur in males. It can be tested for, but there are seronegative people out there with it. 21 patients is not a very large cohort. Notice the mean age was 50...most of the diseases listed occur in that age group. PNs typically start in middle age. Be careful reading online studies, if you do not have the background to interpret them. Diabetics, or those poisoned by toxins may show PN signs earlier. You can get PN from food poisoning. Toxic well water. Inhalants like paint strippers, or pesticides in the garden or on the farm. You can receive contaminated recreational drugs, including MJ. (pesticides) In fact there are so many causes, some doctors don't even look for them. You can have thyroid problems. You can have drug reactions...statins, fluroquinolone antibiotics, etc. In fact now that this is vaccine season, you can get PN from vaccines.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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10-26-2009, 06:31 PM | #2 | ||
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Junior Member
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And it is particularly scary that it was noted that "the disorder was often refractory to treatment" |
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10-26-2009, 09:27 PM | #3 | ||
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Magnate
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--is not the only one, only the most "common".
I say this as someone who experienced an acute-onset body-wide burning neuropathy of the small-fibers (as finally determined through skin biopsy--EMG and NCV) studies were normal, as was every other test except for the skin biopsy). Mine did start in the right foot, but it was in my hands within three days and all over my body in ten. No etiology was ever found, although autoimmune molecular mimicry is a leading suspect. And--one of the reserachers I've corresponded with--Dr. Moghekar at Johns Hopkins, who has written on sensory ganglionopathy--did say the presentation sounded similar to those who get such "ganglionopathies/neuronopathies". And yes, much of the refractory nature of the problem stems from the involvement of the cell bodies in the dorsal root ganglia, which do not regenerate like axonal fibers can. Still, if the damage is not complete, healthier cells may take over the function of dmaged ones in time. This usually involves the sprouting of entirely new axons, though, and it takes a REALLY long time--not to mention the weird sensations one will experience as these new fibers reconnect. Truly, ganglionopathies are very mysterious, even compared to more common neuropathy presentations. But, while regeneration/recovery is difficult, if the process is monophasic, and does not continue chronically, it can occur, at least to a partial extent. See: http://neuromuscular.wustl.edu/senso...tml#idiopathic http://neuromuscular.wustl.edu/antib...uron.html#sfsn Last edited by glenntaj; 10-27-2009 at 06:06 AM. |
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"Thanks for this!" says: | Kiwiboy (10-27-2009) |
10-26-2009, 10:12 PM | #4 | ||
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Junior Member
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Also, does the fact that my hands are popping off to sleep with the slightest bend of the elbow or arms above the head when I'm in bed mean anything... that seems to be becoming more pronounced also. Is that typical of ganglion involvement? I read somewhere about this problem coming about because of cancer in the body?? do you know anything about that? And finally, why, if all exposure to anything has stopped does it progress? is it a case of once the scale tips in one direction, it just keeps tipping regardless? thank you so much for your knowledge on this. Last edited by Kiwiboy; 10-26-2009 at 10:28 PM. |
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10-27-2009, 01:22 AM | #5 | |||
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Wisest Elder Ever
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Ganglionopathy --is a description of WHERE the problem resides. Notice that there are many different diagnoses in that article. Metabolic, immune, toxic.
This article goes into more detail: http://brain.oxfordjournals.org/cgi/.../full/awp136v1 One thing that does occur in that location is herpes virus. I would get tested for this. If you have reactivation of herpes simplex or herpes zoster, these can be treated with antivirals. Your use of poppers suggests you were in a high risk environment for viral transmission. Herpes zoster typically lives in the ganglions and reactivates. I'd also get tested for Hep B and C, and HIV.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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"Thanks for this!" says: | Kiwiboy (10-27-2009) |
10-27-2009, 02:48 AM | #6 | ||
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Junior Member
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And my poppers use was restricted to safe heterosexual monogamous relationship use. Thank you MrsD for your help |
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10-27-2009, 07:54 AM | #7 | |||
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Wisest Elder Ever
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heterosexual use. Herpes zoster is reactivated chicken pox. You can have herpes simplex dormant for many years, and it will reactivate upon physical stress, immune changes. Viral reactivation sometimes responds to high dose l-lysine therapy. At least one gram a day. Rx treatment involves Valtrex, or Famvir. You can also have neuropathy symptoms from vaccines. It can take up to a year or more to have the reactions. This is due to the adjuvants, and contaminants in them, stimulating autoimmune reaction. When this delay occurs doctors don't consider vaccines, but really they are culprits in many in many chronic diseases. Just search Dr. Len Horowitz vaccine on YouTube or Dr. Blaylock. They explain this in several videos. If you get a Temperpedic type mattress topper, having numbness in hands and arms can be minimized during sleep. But I still get a numb arm now and then even with the topper.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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"Thanks for this!" says: | Kiwiboy (10-27-2009) |
10-27-2009, 07:21 AM | #8 | |||
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Member
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I have no doubt that in the past you were warned that drugs (including alcohol) are toxic and could cause damage to your body. It seems that you are now aware that this warning was serious.
Before you start scanning the web for illnesses that compare with your inner feelings, just consider that you are most probably suffering from withdrawal symptoms. Doctors know very little about the drugs that they so freely prescribe. It therefore follows that they will know nothing at all about the drugs that abusers use, including the quantities taken. Never mind seeking medicines that will help your state of health for you cannot treat poison damage with yet more poisons. Never mind taking supplements that you THINK you may be short of. Blood tests will show if you NEED any supplements. In a withdrawal situation, YOU are the only one who can do anything. Eat a good balanced diet, get exercise, and STAY AWAY FROM DRUGS |
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