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Old 11-02-2009, 01:06 PM #6
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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Based on what I have seen about MDMA so far (one researcher is in my area and was on cable with his studies)..Dr. Galloway

Quote:
Conclusion:
These data show that acute MDMA alters both serotonergic and glutamatergic signaling in the medial
prefrontal cortex and GABAergic signaling in the amygdala. The MDMA-induced increase in prefrontal
glutamate turnover is consistent with the well-known ability of 5HT (via 5HT2a receptors) to facilitate
excitatory tone in the prefrontal cortex. Neurotoxic effects of MDMA in the hippocampus are
accompanied by deficits in both GABA and glutamate levels, which may be associated with the cognitive
deficits of MDMA abuse.......
and......
Conclusion from second paper:
These data are consistent with the notion that MDMA disrupts the metabolic homeostasis of
energy regulation in cardiac tissue. The enduring effects of MDMA on cardiotoxicity as well as
the attendant MR-visible biochemical profile remain to be determined.
both papers abstracts here:
http://74.125.95.132/search?q=cache:...&ct=clnk&gl=us



The effects of MDMA are mostly immediate. If you survive an overdose or heavy use without a seizure or hyperthermia, there is not much to worry about. The only thing I have seen so far is the suggestion that MDMA affects serotonin functions and may cause depression or some permanent damage to the brain and its neurotransmitter systems of dopamine and serotonin.

The effects of Levaquin however, are not rare. Many people are on the net about that drug, some with neuropathies that do not resolve.
example:
http://www.fqresearch.org/ftrf_common_adrs.htm
http://www.fqresearch.org/cns_1.htm
Fluroquinolone antibiotics should not be used first line for minor infections. They are to be used when the risk/benefit ratio determines other agents are not effective.

This link is to one of the abstracts on PubMed.
http://www.ncbi.nlm.nih.gov/pubmed/1...m&ordinalpos=1
It has an email to one of the authors (Dr. Perrine).
I suggest you contact this researcher for more data on the drug.

The net has many sites about MDMA...like this one:
http://www.mdma.net/#mdmatox
__________________
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Last edited by mrsD; 11-02-2009 at 01:21 PM.
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