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-   -   Cymbalta - how long to take effect? (https://www.neurotalk.org/peripheral-neuropathy/110637-cymbalta-effect.html)

filipe 12-20-2009 05:18 AM

Quote:

Originally Posted by mrsD (Post 601414)

Thank you for this explendid information :) . I'm taking Tryptizol now. Can you tell me how much mg should I take? Tha maximum?

mrsD 12-20-2009 05:34 AM

Did a doctor give this to you? It is the doctor's job to monitor you while you take this drug.

Most PN doses are in the 10-25mg range. Some may take 50mg.

Anything higher becomes a personal choice and approaches antidepressant levels. This drug can interact with other some drugs and has a potential for toxicity in overdoses, so typically the dose is kept low if possible. High dosing with this may affect the heart rhythm.

filipe 12-20-2009 05:38 AM

Yes,

It was precribed by a doctor. However, what is strange is that the doctor precribe me a dosage of 25 mg and in the info paper it says the dosage is between 75 and 150 mg. Strange....Do you know this medicine?

mrsD 12-20-2009 05:51 AM

25mg of amitriptyline once a day is the average dose for PN.

I have been reading online that Portugal has decriminalized drugs.

Are you buying your drugs without a doctor's prescription?

filipe 12-20-2009 06:02 AM

Of course not :) It is impossible here.

Tell me what is the reason for your neuropathic pain? Do you know?

mrsD 12-20-2009 06:23 AM

I have had long standing low thyroid functioning (PN started from that 30 yrs ago), and now I have
insulin resistance (pre-diabetes). So far my PN is not progressing, due to diet control, and some supplements.

I also have arthritis, I had a severe nerve damage from a C-section (meralgia paresthetica) which is quiet now finally, and have knee issues. I am just getting over severe left thigh pain from an adductor muscle/tendon tear (this was from a fall). I also have broken sesamoid bones in both feet.

I am no stranger to pain.

filipe 12-20-2009 07:11 AM

I also had a Tyroidite (but very small). And it is controled. I
take Eutirox 025 everyday. hmmm!!!

You don't take neurotin or lyrica? Why?

JoanB 12-21-2009 04:37 PM

Quote:

Originally Posted by mrsD (Post 601077)
Personally I think amitriptyline is a better choice. It shows benefits for peripheral neuropathy healing...that no other drug shares. (this is fairly new). But that is only my opinion.

That's really interesting, mrsD! I'll have to ask my neuro about that.

Update: I've been feeling significantly better the last few days. I occasionally have a not-too-bad day, but never a string of good days in a row like this. I've been on the Cybalta for about three weeks now.

I hate to get my hopes up so soon, but it's hard not to. If it's really helping, maybe I could even taper off of the Ultram. I'll keep you all posted.

Thanks!

JoanB 12-29-2009 03:16 PM

Hmm...posted a few hours ago to give an update (I thought) but now I don't see it. Maybe I clicked the wrong button or...? Anyway, I said before that I'm not sure now if the Cymbalta is helping or not. I've had several good days and several bad days so it's hard to tell overall. I probably should have rated my pain every day when I started this med so I could compare, but I guess if you're not sure, it's probably not helping all that much. Still, like I said, I don't usually have more than one good day in a row so maybe it is helping some.

I started yesterday on the dose my neuro wanted me to get up to (90mg) so I'll just have to wait to see for the next week or two. At least I don't seem to be having any side effects so at least there's that to be happy about.

Raglet 12-29-2009 06:30 PM

Quote:

Originally Posted by JoanB (Post 601054)
Doses I'm currently taking: 60mg Cymbalta 1X a day and Ultram 50mg 6X a day. My neuro said that when using Cymbalta for PN, it's not usually effective until you're up to 90mg a day.

Wow, 90mg seems quite high to me, I am on 30mg as an antidepressant which does the trick for me, though maybe I am just weird (wouldn't surprise me at all).

Hope it does the trick for you

cheers

raglet


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