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04-22-2010, 11:00 AM | #1 | ||
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New Member
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Does anyone have info about alpha lipoic acid (ALA) for chemotherapy induced peripheral neouopathy? Anyone have success with it? Thanks.
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05-02-2010, 12:32 AM | #2 | ||
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Junior Member
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I'm surprised no one's answered you! I did some research on this for a former boss was has some minor neuropathy from chemo. What I found was Alpha Lipoic Acid is certainly used, but more in conjunction with acetyl-l-carnitine and CoQ-10. All of these are supposed to help the mitochondria in your cells, which get damaged by the chemo. Good luck.
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05-02-2010, 06:04 AM | #3 | |||
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Wisest Elder Ever
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Many people here use alpha lipoic acid. I don't know why there are no answers?
There are years of studies on PubMed about it. This is an example of a newer one: Quote:
One has to use at least 600mg a day. There is a newer version called r-lipoic acid. There are fewer papers on this newer version, but it works the same way as the old alpha, only at lower doses. Alpha is racemic mixture, containing r- form, and an inactive other form. Typically the dose of r-lipoic is 100mg a day. It may lower blood glucose, so if you take medications for that, you need supervision.
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05-02-2010, 06:43 AM | #4 | ||
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Magnate
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--though in the last several years I had switched to R-lipoic so I could take less. I went from 600mg alpha-lipoic to 50mg R-lipoic each day, as I found the large amount of alpha made my stomach more acidy than I was comfortable with. The R-lipoic is still acidy, but taking it with food mitigates that.
I take so many things that it's hard to parse out the effects of the lipoic individually, but I do remember getting fewer burning sensations on it than not. I also believe it has helped with blood sugar stabilization--I am not diabetic, but I am insulin-resistant with some degree of reactive hypoglycemia if I don't balance carb intake with protein and fat, and I seem to have more of an even blood sugar response on lipoic. |
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