This thread is about pain receptors and pain relief...

Not about antacid actions on the stomach.

It is about using AlkaSeltzer for its systemic properties for some people.

Keep in mind, AlkaSeltzer has aspirin in it. So those with problems with aspirin, can try AlkaSeltzer Gold, or TriSalts which both do not have aspirin in them.
TriSalts are sometimes used by environmental physicians to treat allergic reactions. The histamine receptor seems to be blocked by basic bicarb... temporarily.

While AlkaSeltzer is less irritating to the stomach lining, it is still working the the blood as an NSAID and anti-inflammatory.

When I use AlkaSeltzer original formula, it is typically at night when I have burning. I DO NOT use it all day long, or even everyday.
If you use it every day, do so with your doctor's approval.

Please read the pain link I gave today above, on pain receptors and acid.

But when you get down to it, on one hand there is an action where acid is burning nerves. I have noticed that my neuropathy is in full gear when my reflux is on high......or after a day or 2's bout. Even more so when my I have twisted my body in some direction or done some new activity that feels as if I have opened up the damaged(nerve) area to stomach acid. Meaning if you have persistent reflux and are keeping your stomach insulated with the herbs I mentioned, you should not have this problem as much and should not have to use drugs which make it worse.

Not saying Alka Seltzer is terrible, but those approaches I listed above are very popular natural approaches for acid reflux. Acid Reflux seem to be good friends with Neuropathy. First the burn in your stomach and then in your nerves. Anybody notice reflux/neuropathy worse in the summer? Ergo the connection. Enjoy!

I am sorry I don't agree....

AlkaSeltzer is not a good choice for reflux. Never was, never will be.

I fixed my GERD, over 12 yrs ago, using essential fatty acids...
ONLY. I had a terrible X-ray showing a severe hiatal hernia, which I still have, refluxing right there at the test (which my doctor says happens less than 10% of the time).
I was born with a rare defect in the GI tract that causes it to be twisted into a unnatural rotation. It is not fixable at yet, and maybe never.

My reflux is gone, and I don't use antacids or drugs for it anymore. I fixed it in 3months.
In fact this result was what sent me on the path I now take.
I also fixed my son's ADHD with the same result.

http://neurotalk.psychcentral.com/showthread.php?t=6092

This is simple, really.
Also much of GERD, reflux, is mechanical, and due to gas.
Gas pushes stomach contents up, when you lie down. So some dietary modification, avoidance of acid reducing drugs, like PPIs and H2 receptor antagonists, can help with this issue too. That is because when stomach acid is neutralized or blocked, you cannot break down protein in food, and that ferments in the GI tract and comes back up as gas to reflux you.

The burning in my feet is totally independent of any heartburn. While poor EFA status may contribute to nerve's burning in the body, and also to GERD... GERD does not cause PN (except for blocking B12 with anti-GERD drugs long term.)

I think the combination of Lexapro, Finasteride, Xanax and Prevacid really did me in. The Finasteride weakened my adrenals and and hurt my body's ability to repair itself. The Prevacid stripped me of B-12 which is essential for gut health. The other drugs took away my ability to feel the pain and mind health cues. That is when the nerves starting burning.