I have tried Neurontin and Lyrica several times with bad effect. When I tried the Neurontin last time, I started at a dosage of 300 mg/day. I did not notice any improvement in my pain at that dosage - even after two months time. When it was upped to 900 mg per day, I did have some small relief in pain though the side effects were pitted edema and confusion/irritability. I noticed the confusion/irritability with the smaller dosage as well. The slight improvement in pain and pitted edema occurred rather quickly after the increased dosage - perhaps within one week. Therefore, it was discontinued. Hope this helps.

I have been successfully taking Savella, 50 mg bid for three months now. I hope it continues to work without fall off. I also take Lortab - 1-4 tabs per day for pain depending on my pain level. I do have several pain issues including the SFN, dysautonomia, FMS and undifferentiated AI/arthritis disease. The pain medicine helps me to maintain a more active lifestyle, although I am still on SSD (and wish I were not). I have been on Lortab for many years. Successfully, I might add, meaning: I have not required an escalation in dosage, my liver is still functioning well without an increase in liver enzymes, and I automatically take less of the drug if I am feeling better. I am sure that I am dependent on it, but not addicted. The same doctor has prescribed it to me all along.

Mere