Thanks to one of our members, was directed to the Quest Diagnostic list of Laboratory Diagnosis of Peripheral Neuropathy tests.

Known for 8 months via skin punch biopsy that I have small fiber neuropathy. Very early on was Rx'd neurontin, Lyrica and Pamelor (first two were intolerable! in the extreme and Pamelor did nothing). The neuros didn't go any further with me; the first two didn't even say come back for a follow-up (Cleveland Clinic), and I live only about 25 minutes away from the main campus.

This same NT member pointed out that although the SFN is known, it's not a cause and sometimes this set of tests can determine the etiology of peripheral neuropathy. That could then point the way toward an appropriate treatment to "tamp down," as explained to me, the neuropathy and hopefully keep it from escalating.

So I'm going to request them.

Has anybody else had these tests, what was the outcome and if any were positive, what was the Dx and treatment? They are autoantibodies to peripheral nerve antigens:

Anti-Asialo-GM1 Ganglioside neuropathy, anti-GD1a ganglioside neuropathy,
anti-GD1b ganglioside neuropathy, anti-GM1 ganglioside neuropathy, anti-GM2 ganglioside neuropathy, anti-GQ1b ganglioside neuropathy, anti-MAG/SGPG neuropathy, anti-sulfatide neuropathy

Best wishes,

Sheltiemom