Lynn01

You have sensory and motor involvement so do you get cramps and or twitching with it.

Thanku

Sometimes cramps in the feet, my toes will cramp sometimes and look distorted. not really twitching of muscles. My legs feel like rubber at times, it's just not a normal feeling and my left knee feels floppy and my ankles feel weak. I have mild tingling and numbness in the feet and occasional sensations about midway up the calf.

Okay thank you Lynn.

It can manifest differently in everyone I guess.

For example my left leg. Inam felling prxhes of numbness to stocking feelin to migrating stabs to in and out crMps to sudden twitching which can be one twitch to like a machine gun goin off. Always feel the twitch coming agterthe severe stabbs. So I have severe twitching too which is not painfull. And they can be in Tiniest fibers like a dot of an area or huge muscles. (now this happens head to toe migrating or All at same time)

i am officially ideopathic although i know it has a toxic cause due to exposure to numerous toxic substances(not medicines) nine years ago. By the time i realized what i had was PN it was really too late to test for those substances.

Tulips i have sensory motor PN also and i also get fasciculation in my leg muscles often. I also get muscle jerks in my arms and legs. The strength in my legs and arms has not diminshed that much. I also get severe cramps if i dont keep up with taking magnesium or drinking enough water. My toes will also cramp if i contract them. My feet are pretty much dead numb now with numbness going above my knees. At the same time though when i stand or walk it feels like i am walking on broken bones.

If neuropathy is caused by meds can it ever heal.

I think mine could be autoimmune or hereditary since sister with ms plus my history of allergies and eczema.

If skin biopsy is normal does that mean I don't have sfn or does it mean there isn't damage yet?

Your first question:
Some drugs (HIV drugs and chemo) do recover if the patients use acetyl carnitine. These two families of drugs cause PN.
I have not seen studies on healing PN from Statins. (some people who come on these boards, have improved, others not.)
Drugs like Flagyl, some posters here are not showing improvements. Fluoroquinolones I have posted anecdotal information on my Subforum thread.
I have seen reports of improving alcoholic induced neuropathies with B vitamins, and diabetics are in the studies currently using
alpha lipoic acid and acetyl carnitine and benfotiamine (a form of B1).

Your skin biopsy results only shows a window of time when the biopsy is taken. It does not show what you had before, or what the future holds. The results are averages just like for blood testing. It will give an idea, but nothing definite.

I think you need to start that gluten free diet while you wait for results. If your culprit is gluten, you can see small improvements within a month.

You absolutely must read more and study up. Much of what you can do will have to come from YOU, and not doctors.
Check out the stickies on our Gluten forum for excellent links to help you. There have been many people here over the years with gluten induced neuropathies who have improved and moved on to the gluten free communities on the web.
There have been a handful of misdiagnosed MS patients too.

This site has a special section on gluten intolerance inducing neuropathy:
http://sites.google.com/site/jccglutenfree/

Thank you mrs D

A lot of this stuff goes over my head. Any case will read on. Most of every test I researched and demanded. They were about to do a genetic pod test for different ones that Athena offers an that when I lost my insurance!

I am going to get the glucose tolerance done next week. Will be paying out of pocket. Hopefully wont be too expensive.

You know every where I read it says that when doing skin biopsy for neuropathy two or three spots of skin are taken from different parts of leg but my doc only took one spot on my ankle.

I tried gluten free when I did the detox nutritional stuff for 21 days and didn't see any difference and gave up but I have realized that's not enough time.

Plus the natrual medicine doctor did body impedance test. Never heard of this before. He put electrodes like EKG and recorded results. To tell me if I continue this way my healing level is down!! What ever that means

Thanku

I have congenital spinal stenosis of the lumbar and cervical disk bulges pinching nerves causing the peripheral neuropathy in hands arms feet and legs.I have also had it flare up in my trigmenal nerve on my face. Man did that hurt.

I get cramps also. Usually the feet or sometimes the calves. I also have the "strange" feeling in both legs along with tingling and numbness. The tingling can get intense enough that it hurts or sometimes burning.