well, actually the generic of it, is working well for me, I have been able to cut down to 900mg. of Gabby because of it. It does make me tired, but I take
30 mg. at bedtime, works out well........don't need Valium to sleep anymore.

Just wanted to share that, I know some of you are having trouble with tolerance issues with Lyrica and Gabby, as I was experiencing also.

I am glad that is working for you. Elavil remains the best option today for neuropathy because of its potential for healing nerves.

The other drugs do not have that benefit. Most people become used to the sedative actions, and when kept at a low dose, the blurred vision and dry mouth are much less.

MrsD- You commented on ... the potential for healing nerves. I saw something similar in a medical publication and asked my PN specialist about it? He seemed surprised and asked for an exact reference. So I later found it and forwarded it to him. No response. Do you know of any follow-up work or think there is a good avenue for pursuing this?
I currently take 75 MG's each night which dulls the pain for me.

Sorry, it was just a new finding. Takes a while for others to set up studies to confirm.

To produce healing. Would you be able to post the link/info?

That is pretty exciting news.

http://neurotalk.psychcentral.com/sh...=amitriptyline

have now tapered down from 300mg lyrica to 75mg.

have finally settled on amtryptoline very low dose 10mg.

I have less pain then when the doc initially put me on 300mg lyrica and 25mg nortyptoline 2 years ago.

The swelling in my feet has gone down which i suspect was not from neuropathy but lyrica. My worst pain days were when swelling was highest compressing the nerves.

I will have lyrica out of my system next week.

Anyone else tried tapering down without consulting the doc? Just have a feeling that many are taking a large dosage of drugs that may not be effective anymore but continue anyway.

If the R-Lipoic is working on PN pain & burning, (making gabapentin unnecessary) does/would it make sense to take amitriptyline anyway for this effect?

Doc

I really don't know.

The natural approach is correcting something that was wrong, and doing so very quickly for you.

I think you should continue the lipoic for at least another month, and then stop. See if the symptoms return. If not, that would show healing IMO.

You can take them together, but I would do a test like above, first to learn something about your symptoms.

You might want to try some antioxidants too-- the powerful ones. They also trap free radicals and help with inflammation.

MegaRed Krill oil with the astaxanthin and grapeseed extract.
You can buy the astaxanthin separately now, and neither is expensive. Something to think about.

Lipoic acid also reduces blood sugars and that may be happening too. Lipoic acid is added to "mitochondrial support" supplements to aid acetyl carnitine in them. So it has several functions.

I was thinking benfotiamine next, followed by CoQ-10, spaced apart so I know what's what.

Doc