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Old 02-16-2011, 04:10 PM #1
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Default Is anyone familiar with "Gapapentin ER" - the time release version of "Gapapentin"?

Is anyone familiar with the time-release version of Gabapentin, which I believe is known as "Gabapentin ER"?

As anyone knows who has used the regular version of Neurotin (AKA Gabapentin), it can cause one to become drousy or "loopy".

As such, I was intrigued when I saw that an extended-version form of the drug was now available (the "ER" version).

Is anyone familiar with the "ER" version, and is it logical to assume that using the "ER" version (with a presumabily slower and steadier drug release) might result in less drowsiness?

Mrs. D?

Thanks!

David
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Old 02-16-2011, 04:27 PM #2
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Here is an article about it:

http://www.drugs.com/newdrugs/depome...etic-2514.html

I wonder how well it will work, since gabapentin already has poor absorption and bioavailability in immediate release?

I don't think it is available here yet.
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Old 02-16-2011, 05:08 PM #3
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Quote:
Originally Posted by Apollo View Post
Is anyone familiar with the time-release version of Gabapentin, which I believe is known as "Gabapentin ER"?

As anyone knows who has used the regular version of Neurotin (AKA Gabapentin), it can cause one to become drousy or "loopy".

As such, I was intrigued when I saw that an extended-version form of the drug was now available (the "ER" version).

Is anyone familiar with the "ER" version, and is it logical to assume that using the "ER" version (with a presumabily slower and steadier drug release) might result in less drowsiness?

Mrs. D?

Thanks!

David
Hi David,

It's called Gralise. The side effects listed are the same as for gabapentin, though the percentages of patients affected may be different(couldn't find exact numbers for gabapentin).

The big question is, as an "orpan drug", will it be worth the presumeably heftier pricetag?

Doc
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Old 02-16-2011, 09:44 PM #4
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Quote:
Originally Posted by mrsD View Post
Here is an article about it:

http://www.drugs.com/newdrugs/depome...etic-2514.html

I wonder how well it will work, since gabapentin already has poor absorption and bioavailability in immediate release?

I don't think it is available here yet.




.... it looks promising ... thank you for your thoughts!

David
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Old 02-17-2011, 08:52 AM #5
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IMO-Since the Neurontin is now available in generic gabapentin form and the Neurontin is out of patent, they gotta 'sweeten their pot' with a newer form that they can charge bigger bucks for.
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Old 02-17-2011, 10:01 AM #6
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imo-since the neurontin is now available in generic gabapentin form and the neurontin is out of patent, they gotta 'sweeten their pot' with a newer form that they can charge bigger bucks for.
Exactically!
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