It is really hard to say.

If the process creating the damage continues in some way, there will always be damage. You could pace it, and 1)heal at a rate that may be higher than the damage causes,2) they stay the same rate so you may see no progression, or 3) less which would lead to progression of symptoms.

We don't know enough about what is causing damage in say Sjogren's or seronegative MG or MS etc.

People who stay ahead of the damage by using healing supplements, may relapse when they go off the supplements used. (since the process causing the grief is continual).

The studies on ganglioneuritis and the damage to nerve fibers in the ganglia which may be a genetic weakness, or viral, may shed some light on this. Stem cell therapy or something similar may be discovered in the future.

We just know that there are studies showing improvements using various supplements...and that's all we have to go by at this time.