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Old 09-18-2011, 03:02 PM #1
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Default question for any experts out there about alcohol and nerve repair

Hey everyone,

So I have been trying to heal from a groin based peripheral neuropathy due to trauma that has been going on for about 1 1/2 years. I really cant say If im seeing any progress at this point still...

Anyways, during this time I have also been sober from all alcohol and have not smoked at all due to my desire to be in optimal health to help the nerves regrow (which I dont even know if they will at this point).

So, Ive been wanted to drink socially here and there, like a cup of wine or something, but I am paranoid that it will inhibit the potential growth of any nerves.

My question is, would a *small* amount of alcohol on a *very limited* basis interfere with my nerve's ability to regrow?
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Old 09-19-2011, 09:22 AM #2
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Hi John, I'm sorry I can't answer your questions, but I do have a suggestion.
What about when going out with friends you drink a non alcoholic drink.
My hubby was alcohol dependent and has not drank now for 14 mths. When we have had to go to social occasions my hubby will drink non alcohol larger. You will have to check the labels though as some say they have no alcohol content when some do have a small amount.
Hope this is of some help.
Regards
Buttercup
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Old 09-19-2011, 11:16 PM #3
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anyone else have advice/thoughts?
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Old 09-20-2011, 09:08 AM #4
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Lightbulb

For many years some experts have said, that only alcohol abuse affected nerves thru poor nutrition. Improve the alcoholism and you improve nutrition, and many therapies involve B complex vitamins. Specifically B1.

However there is a new study showing direct damage in animals from alcohol itself to neurons.

So it is difficult for anyone to really say if you should avoid all alcohol or if you could have a small amount occasionally.

Here is a pretty good comprehensive link:
http://emedicine.medscape.com/article/1174146-overview
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Old 09-20-2011, 11:27 AM #5
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thanks once again Mrs.D

was looking over that link and saw this

•Studies in rats also failed to demonstrate a direct toxic effect of alcohol on the peripheral nerves


could you post a link to that new study u r reffering to? Thanks so much.
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Old 09-20-2011, 11:36 AM #6
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Red face

I'll look for it.... it is on this forum in fact.

But I've been very ill with a GI thing and feel rather awful, still.

Weak and the strong antispaz medication makes it hard for me to think sharply like I do normally.

I'll look for it...did so this morning some, but gave up. I'll try to find it for you by tomorrow.
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Old 09-20-2011, 12:49 PM #7
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Here is one:
Quote:
Arch Med Res. 2009 Jul;40(5):325-30. Epub 2009 Jun 26.
Impairment of peripheral nerve healing after nerve repair in rats chronically exposed to alcohol.
Ertem K, Ceylan F, Zorludemir S, Karakoc Y, Yologlu S.
Source

Department of Orthopaedics and Traumatology, Faculty of Medicine, Inonu University, T. Ozal Medical Center, Malatya, Turkey. kertem@inonu.edu.tr
Abstract
BACKGROUND AND AIMS:

The aim of this study was to determine the effect of chronic alcoholism on the healing of repaired peripheral nerve and muscle.
METHODS:

Group 1 rats (n = 9) were fed with an alcohol-free modified liquid diet (MLD) throughout the experiment and received no nerve transection or repair. Group 2 rats (n = 9) were fed the same isocaloric MLD and underwent nerve transection and repair. Group 3 (n = 7) consisted of alcoholic rats without nerve transection and repair and Group 4 (n = 8) consisted of alcoholic rats with nerve transection and repair. To assess the effects of chronic alcoholism on nerve healing, surgical procedures were applied to rats in Groups 2 and 4. After 2 months, posterior tibial nerve and gastrocnemius muscle samples were taken for histological analysis.
RESULTS:

Group 2 rats displayed a group of atrophic fibers, whereas Group 3 rats showed myophagocytosis and endomysial mononuclear infiltration and type 2 fiber atrophy. Group 4 rats displayed a large section of atrophic fibres. Axonal loss, prominent regenerative clusters and endoneural fibrosis occurred in Group 2 rats. Axonal and myelin degeneration, myelin remnants and thinly myelinated axons were exhibited in Group 3 rats, whereas severe axonal loss, myelin degeneration, regenerative clusters and endoneural fibrosis were discovered in Group 4. There was a significant difference in the number of myelinated axons among the various groups of rats.
CONCLUSIONS:

Our findings show that chronic alcoholism has a negative influence on peripheral nerve regeneration associated with a significant decrease in axon number and increased axonal degeneration.

PMID:
19766893
[PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/19766893

This is all I could find at the moment.
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Old 09-20-2011, 02:37 PM #8
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Quote:
Originally Posted by mrsD View Post
Here is one:


http://www.ncbi.nlm.nih.gov/pubmed/19766893

This is all I could find at the moment.

hmm that talks about alcoholic rats which I assumed were being fed alcohol for every meal. Im talking about once or twice every 2 weeks or something.

I know when I first got the injury, I was a complete alcoholic and was drinking every day. This went on for a year after the injury.

Do you think the damage is now permanent?
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Old 09-20-2011, 04:15 PM #9
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As I said before this is difficult to answer.

My impression is that if you had alcoholic induced PN you would have it elsewhere as well. But yours is confined to a tissue injury site only.

No one here can say for certain what you should do about recreational alcohol use.

Some tissues when damaged never are the same again.

For example:
My surgical foot was very numb on the instep for many years where the long scar is. Then feeling came back so I could feel the skin there slowly. And now that I am older that ankle swells up for no reason, and the area of the scar hurts. I don't know why and none of the doctors I asked know either. I just get hmmmmm and blank looks.

Some things "just are" following an injury or surgery.
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