Now please don't laugh but when he brought this up, the first thing I thought of was "I'll ask the people on the boards".

Alan went back to the gym for the first time today (since he got home from the 5 rounds of IVIG). Today, he got his strength back and he went.

So he just got home and he's lying down and relaxing and I asked him "did you use the steam room". He said "No, I was afraid" I said "of the steam room??, why on earth are you afraid, it sweats out all your toxins, 5 to 7 minutes in the steam room will do you a world of good". (and he usually goes in the steam room anyway)

His reply: "I was afraid the new antibodies that I got from the IVIG would be sweated out of me and I would lose them". I started to laugh, then I said "you know, what the heck do I know, does a person sweat out antibodies??". Especially EXPENSIVE ANTIBODIES???? Might be a stupid question, might not.

So, while I'm sure he can go back into the steam room, he just want to make sure.

Thanks, Melody

Melody,

I have no clue! I just wanted to pop in and say when I read this, I was laughing so hard! But it is a legitimate question...I would probably wonder the same thing too.

If you think you're laughing, you should have seen my face when he first asked me. I had to hold my mouth closed.

But honestly, if you think about it for a moment, I mean, he wouldn't go into a steam room because he was afraid his anti-bodies would sweated out.

Don't we continuously make new antibodies? But if Alan has an anti-body problem, and he's not making GOOD antibodies, then it might not be such a strange question after all!!!!

SOMEONE JUST TELL THIS GUY HE CAN GO INTO A STEAM ROOM, and all the little nanobots going though his body aren't going to be jumping on the floor.

lol

mel

I cannot tolerate the steam room with my PN! It is amazing that Alan can!

Can Alan go into the steamroom while he is undergoing IVIG???

Tomorrow Dr. Goldfarb is supposed to call up Alan and schedule his first home infusion. So before this happens he wants to go the gym and do his stuff.

So can he use the steamroom? Or do all the little antibodies end up on the steam room floor after all????

Mel

--but to my knowledge, the amount of antibody that could be sweated out under steam room conditions is negligible.

Antibodies are specific protein chains--one of the reasons autoantibodies are sometimes referred to as "rogue proteins". They are rather large chain molecules and would not easily pass from serum/plasma through to the cutaneous levels--unless they had already, for some reason, been broken down into component amino acids, in which case they would have already lost their effectiveness as immune agents, anyway.

Think of it this way--if it were possible to sweat out large quantities of antibodies under hot/humid conditions, those people with autoimmune conditions would be flocking to steam rooms and the tropics to reduce their antibody titers, but there's never been any evidence I know of that increased temperatures/humidities reduce autoimmune symptoms. In fact, it IS well known that for many conditions of nerve, heat/humidity actually makes symptoms worse--heat is the enemy of nerve conduction (it tends to increase the electrochemical resistance of the nerve cell membrane and makes it harder for the ionic exchanges to occur). Well-insulated (myelinated) nerves can overcome this, but those with myelin damage . . .cooling vests are very popular among multiple sclerosis patients.

So, if he can otherwise tolerate the steam room, I don't see any reason Alan's visits there would make his IVIg less effective.