I happened upon a post by Mrs D yesterday. This was before I knew about this forum & before joining. It listed Solgar Folate, Jarrow Methyl B-12 and Now Foods P-5-P as substitutes for Metanx. I've been taking Metanx for about 2 yrs, but not originally for PN. A podiatrist prescribed it for a SEVERE foot itch that happened every 3-4 months but would be so intense I often scratched myself raw. I can hardly begin to describe the pain of this itch. Fortunately, the itch never occurred when I wasn't home because I'm not sure what I'd have done. The Metanx has basically stopped this. I've had the itch maybe a couple of times, but not nearly to the severity as before. Then several months ago I started having an occasional odd feeling in my feet and sometimes hands. No pain, just something not normal. Went to the doc and he referred me to a neurologist. After nerve tests, he said I have a mild case of PN and thought the itch had been the beginning of it. He prescribed Celebrex which I'm not taking. Since I have no real pain or disability from the PN, I didn't want to take something like this. I continued with Metanx. But the price is escalating like crazy, so I was happy to see the supplement alternatives. Went to a nutrition store yesterday and bought the B-12 and folate. The man there, who seemed VERY knowledgeable, suggested that instead of the P-5-P I should use Life Link Primage. Said studies on cats :-(( had shown that nerve damage repaired itself. Said it also helps with symptoms of aging, diabetes, etc. I don't have diabetes but have blood work done at least twice a yr to monitor it since my sugar level is between 106 and 110. I started walking nearly daily about 4 months ago so am hoping the next blood work will show that's been reduced. Sooooo, all of this is to ask -- mainly I'd like to hear from Mrs D -- what you think of this Primage instead of the P-5-P. Also, this guy suggested TMG so since it wasn't expensive, I bought it. Haven't opened any of these so can return the Primage or TMG if you don't think they're worth taking. I REALLY want to keep this itch away!!!