Originally Posted by glenntaj (Post 834230)

....some papers are cited, that seem to indicate that while non the first line of medications recommended to combat neurological pain (that line includes the anti-epileptics and anti-depressants, which have specific neurotransmitter mechanisms), opiods, and opiod analgoues such as Tramadol, are effective in SOME people in controlling neuropathic pain.

Like may other meds, they work for some (often in combination with anti-epileptics and/or anti-depressants) and not for others.