Originally Posted by en bloc

That is sad to hear this. Repeat biopsies (especially after a course of treatment) to gauge improvement or disease progression is one of the best features of the biopsy.

How else can they tell if the fiber density has increased or gotten worse? You could consider printing some of the documentation that supports repeat biopsies...if you think they would even read it or be open to the idea. New medical technology does no good when doctors stop being teachable.

Originally Posted by JHop11

It wouldn't make any difference in treatment/management to have a second Bx. Even if the biopsy showed improvement, and someone is still experiencing symptoms, they're treatment will stay the same. Biopsies are not always used to monitor clinical progression. sometimes they are simply used for diagnosis.

Originally Posted by glenntaj

--is high.

Moreover, the big drop from hour one to hour two does suggest at least a degree of reactive hypoglycemia.

A draw at one-and-a-half hours would have been interesting to see, as would concomitant insulin levels along with the blood glucose level draws; I bet there would have been a big insulin spike, probably "out of range", somewhere around one to one and a half hours.

Originally Posted by SFNgirl

Hi, this is my first post, am totally new to this sort of thing. I started reading your posts over the last few weeks and decided I should join. You all have provided so much helpful information, very appreciated for the newly diagnosed.

I began having back pain and nerve symptoms last October, and after months of tests, was diagnosed in january through skin biopsy with idiopathic small fiber neuropathy. I have gripping pain in my feet and freezing burning pain in my feet, legs, torso, back and neck. My hands mostly just go numb periodically, mostly at night in my sleep. In the midst of this, in December, I had an extremely painful attack in my face which took me to the ER and was diagnosed with trigeminal neuralgia. In hindsight, my doctors do not believe its that but somehow related to the rest. Have any of you had this connected to your trigeminal nerve?

I am taking 2700 mg of gabapentin, Tramadol, Nortriptyline at night, and just finishing 2 month trial of steroid infusions. None of it seems to help.

I have seen mention from a few of you about a smaller subset of non length dependent type of SFN, given my body wide symptoms, am wondering if I fit in that category. And if so, is this something to pursue that might lead to an identification of an underlying cause or different treatment plan?

Thanks for listening,
SFNgirl

Originally Posted by GeorgeQ

hello janieg, wondering how are you after these years and if you found anything new in the mean time. I am pretty sure I ma suffering from SFN as well

thanks