[Stacy2012]

I wonder the effect of hormones on our PN. I have mentioned this before maybe, but it has become even more glaringly obvious that hormones influence how bad my PN is during certain times of the month.

I have never found anything on the net about it but I sure do believe it to be so.

Great, another reason to want to avoid certain times of the month, lol

But the correlation of hormones to PN makes me wonder on a wider scale even for men and/or women who no longer have their periods, what the effect of certain levels of hormones are to effect PN.

[Marlene]

Progesterone has neuro-protective action from what I recall. You can search on progesterone and neuropathies to find more info.

So it makes sense that your monthly cycle will effect how you feel.

[Stacy2012]

Interesting, since you mentioned it I googled it:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085268/


Conclusion:

These results indicate that progesterone, when administered immediately after nerve injury, and for a sufficient period of time, can prevent the development of neuropathic pain, and may offer new strategies for the treatment of this highly debilitating condition.

There is much more in the link, interesting reading.

[Dr. Smith]

I don't know about PN per se, but hormones can definitely have an effect on chronic/intractable pain. The supporting articles can be found in this thread:

http://neurotalk.psychcentral.com/sh...ht=preliminary

Doc

[Stacy2012]

Wow great thread thanks for posting!