To my great surprise, I had breakfast with a cousin of my husband's who mentioned he had a problem with neuropathy in his hands and feet periodically and tried Jarrow Neuropathy Support and it helped him. He is friendly with a distant cousin who has the same problem, and told him about it and it helped him.

This is not my side of the family. I'm having problems with my foot and using a cream that is helping....Kerasal Neuro....(name just escaped me....but it has helped significantly!)

BUT, I just had a bladder infection and am now having pelvic spasms and this happens now and again and sometimes I wonder if it can be nerve related. Hurts like the dickens, but fortunately, it only lasts about three weeks.

Well....this tablet by Jarrow has R Lipoic Acid in it. Anyone try this tablet and get relief? Anyone use R Lipoic Acid and get relief? Any potential negative side effects to R Lipoic Acid???

Thank you.

Yes, R-Lipoic Acid stopped the burning pain for me within a couple days, and it hasn't been back since except briefly via triggers. My results are atypical; it usually takes a few weeks.

The only side effects I'm aware of at the levels recommended for PN (100 mg/day) is possibly an acid stomach or heartburn, and possibly lowering blood sugar slightly. I've only gotten heartburn a couple of times in the 3 years I've been taking the RLA, and a couple of antacids fixed that.

See also: r-lipoic acid side effects

In one study, 28 out of 33 patients (84.8%) previously treated with alpha-lipoic acid for peripheral polyneuropathy reported further improvement after combination with pantothenic acid (vitamin B5). I take B5, and I've noticed further improvement in reduction of shocks/needle jabs.

As far as the Jarrow product goes... http://neurotalk.psychcentral.com/post1034908-327.html

Doc

I take Jarrow B12 but not the formula you mention here.

I also take 100mg of RLipoic Acid now. I tried it a year ago and could not take it, caused severe heartburn, but now I take it with a half teaspoon of baking soda and so far no problem, been over a month.

Burning is severe for me and some things have helped but nothing cures it. Benfotiamine use to make it go away then quit. RLipoic acid has done nothing so far for me so far as I can tell...not even sure I should keep taking it.

Zyflamend has helped a lot but as with befotiamine the longer I am on it seems it is not working as well but it does still help.

It's like my body adapts to anything that works at first then it wears off.

I don't know, but I can't help but wonder if the baking soda might be neutralizing the RLA.

Doc

The RLA is in the form of sodium lipoate, in the Stabilized form.

It is absorbed that way. It is not an acid. And according to the manufacturer of sodium lipoate, it is absorbed very quickly too in that form.

MrsD are you saying I should or should not take baking soda w it?

Vowel Lady.
Here are some interesting information I came across on the Web the other day. This is in regards to what you mentioned in your post regarding pelvic spasm.:
I came across a web page seems to be posted by a OBYGN group of doctors. They did a study on some women age 24 - 64 who had volvudyna.
They did Autonomic testing for small fiber neuropathy . They did the QSRAT test, found that 10 out of 17 of the women had results consistent with small fiber neuropathy.
I tried, but I am not able to enter a link on this. But the name of this doctor company is: SOHO OB-GYN. there ia a contact e mail for drharris@sohoobgyn.com.
This is interesting, because ( this is a little personal) 2 years ago. my first symptom of peripheral neuropathy was related to symptoms re. urinary, gyn.
But I did not know at the time. I did report it to urologist and neurologist. Later the symptoms of SFN increased and traveled down my legs. ( opposite diresctions, most doctors says !)
But, it is known that peripheral neuropathy first symptoms are in distal portions. Well, as I learned, the sensory nerve of the vulva the Prudendal Nerve ends here, and small fiber neuropathy can occur therfor.
Vowel Lady, I realy hope you will be able to find this site, or perhaps Mrs D can. or perhaps Dr. Smith can.
Enter: Autonomic Testing for Small Fiber Neuropathy in Volvudyna Patients.

I hope the site can be found and printed in this forum.

I found a couple of sources that claim the lipoate is produced by mixing lipoic acid powder with NaHCO3 (sodium bicarbonate) in water. The resulting lipoate allegedly has a neutral pH (couldn't find an exact value), so I'm wondering why it still causes heartburn in some people unless some other reaction is occurring when it hits the acidic gastric juices(?)

Doc