I took Tramadol and Tylanol for 10 years for Restless Leg and insomnia, and then for RLS, insomnia, and fibromyalgia. It worked great until... it stopped working. I had no side effects when I stopped. But have had no happy solutions since. I've tried Celexa, Cymbalta, but Tylanol seems to be the best, though not perfect by any means.

http://neurotalk.psychcentral.com/sh...52#post1093052

Doc

SSRI antidepressants can cause derangements
In dopamine levels (lowers it)
Which results in RLS type movements
In the legs, neck spasms, mouth and tongue
Movements that resemble Tardive diskinesia.

You can Google this --
"SSRI movement disorder side effects"

I take 30 mgs of Cymbalta daily and have for about 5 years. It helps me with the pain, yes. It would be a lot worse without the Cymbalta. So far I've not had to up my dose.

I have no side effects from the Cymbalta at all. I went from 75mgs of Effexor a day directly to the 30 of Cymbalta. So I wouldn't have had or rather expected any side effects. Give it a few weeks. The sides should ease. And if not, than the drug simply isn't going to be a good one for you. It can take 2 to 4 weeks or so for the side effects to go away. And even then, if your doc wants to up the dose you may experience a bit of the same side effects again for a few days, at that time.

I also take Ultram (Tramadol). It mutes a lot of the nerve pain for me. It doesn't work for everyone and there are drugs that are much more...disruptive, shall we say? Like true narcotics such as Vicodin. I've been taking Ultram for about the same amount of time as the Cymbalta. I can't take gabapentin (Neurontin) because it makes me suicidal and that's the first line drug given for PN.

Unless they figure out some way to heal the nerves and prevent any further damage medications and such are the only recourse we have as far as I know. I look at it as sort of like being diabetic and needing insulin. I need these medications to live a semi-normal life.