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Old 08-11-2014, 06:36 AM #4
glenntaj glenntaj is offline
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glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default There's certainly a lot of evidence--

--that celiac/gluten sensitivity can have neurologic manifestations, including peripheral neuropathy (most often a small fiber neuropathy that often is not confined to the distal extremities but may occur on the trunk of the body and face as well).

There are also problems with gold standard celiac diagnosis--many gastro doctors not familiar with the endoscopy sampling protocols often do not take enough samples, or limit their sampling to the duodenum, and may miss more patchy villious atrophy.

Typically, though, celiac neuropathy is not treated with immune suppresant drugs, as the autoimmune response here is directed at the gliadin antigen which cross reacts with epitopes in the villi and other bodily tissues. The standard approach is simply not to introduce that antigen into the system after a diagnosis--e.g., abstain from gluten.

You likely should have been offered a serum celiac panel earlier; now, though, if you've been off gluten for a while, the test results may not be accurate.
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