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-   -   B6 High Blood Levels (https://www.neurotalk.org/peripheral-neuropathy/216070-b6-blood-levels.html)

16rhonda 02-26-2015 08:33 PM

b6 levels ??
 
My Dr wants to check my levels in a month. Maybe I should ask to go to different lab?
I was told to stop taking all vitamins. I'm continuing to take my vit. D, E, C, fish oil and biotin. I dont see how these would make it worse.
I have a ? If anyone knows. If your liver cant break down b6, does this mean your livers not working properly?
I read that b6 is water double, so how can u overdose w this vit.?
I did notice my urine was very yellow a couple hrs after Taking a High Potency Multi.
So I assumed my body was excreting the extra B vitamins.
:confused:

mrsD 02-27-2015 09:30 AM

Some B6 is stored in muscles for short periods of time to aid in metabolizing glycogen. It is stored as pyridoxal --the active form and not pyridoxine as is found in most vitamins.

The enzyme in the liver that converts pyridoxine to pyridoxal phosphate, is called pyridoxal kinase. It has been found to be blocked by some drugs. But not all drugs have been studied in this regard. Pyridoxal kinase uses as a cofactor the Vitamin B2 which is riboflavin. If this is low, then B6 cannot be activated properly.

And yes, typically the high dose B complexes are excreted quickly in the urine. The bright yellow is usually the B2 riboflavin showing up. If you take B6 alone, the urine would be lighter with a greenish tint. Excess B1 can give a yeasty odor to the urine or sweat.

I think taking the others you list would be ok, unless those are being tested also.

16rhonda 02-28-2015 02:25 PM

re: B6
 
Quote:

Originally Posted by mrsD (Post 1126317)
Some B6 is stored in muscles for short periods of time to aid in metabolizing glycogen. It is stored as pyridoxal --the active form and not pyridoxine as is found in most vitamins.

The enzyme in the liver that converts pyridoxine to pyridoxal phosphate, is called pyridoxal kinase. It has been found to be blocked by some drugs. But not all drugs have been studied in this regard. Pyridoxal kinase uses as a cofactor the Vitamin B2 which is riboflavin. If this is low, then B6 cannot be activated properly.

And yes, typically the high dose B complexes are excreted quickly in the urine. The bright yellow is usually the B2 riboflavin showing up. If you take B6 alone, the urine would be lighter with a greenish tint. Excess B1 can give a yeasty odor to the urine or sweat.

I think taking the others you list would be ok, unless those are being tested also.

Thanks Mrs D for info. I dont fully grasp what your trying to say but anyway u mentioned
bf about there being 2 different lab tests for b6. Serum or blood cell would have different ranges. Is one of these tests more accurate than the other?
Thanks

mrsD 02-28-2015 03:07 PM

Mainstream doctors don't as a rule use the cell tests.

Some holistic ones do however. There is pyridoxal in red blood cells and if they burst during handling of the sample, that is reading serum levels, then a false elevated result occurs. This also happens for potassium. Doctors know this and reorder another test if potassium results are high. The medical term for this is a "factitious elevation".

I really don't put much stock in B6 testing. It is only really valuable for extreme lows.


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