My husband is a 2 time AML survivor and an unrelated donor SCT survivor. He began experiencing PN symptoms shortly after his first chemo treatment,the pain is throughout his body including his face and teeth. He has been experienceing debilitating leg cramps and severe muscle wasting. (He eats 3500 calories a day and is unable to hold on to his current weight of 123lbs) precancerous weight was 200. Initially we thought the weight loss and leg cramps were side effects of GVHD but a second opinion has us wondering if these may actually be side effects of PN?