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northerngal 04-11-2015 07:12 AM

That sounds like me when my neuropathy started too. Looking back, I had the twitching a long time before I had any other signs. I just thought it was due to exercising, running etc. I was checked several times for lung cancer due to the VGKC antibody.
The weakness came after the cramping/twitching and I never had any pain.

Ragtop262 04-16-2015 09:03 AM

Before my neropathic pain started, I did quite a bit of research on BFS (also known as "peripheral nerve hyperexcitability syndrome"). In addition to the study I posted earlier, that investigated BFS as essentially a symptom of PN, I also noted that there is often an autoimmune issue associated with BFS - as there is with PN. The difference being that with BFS, the autoimmunity is typically associated with the potassium channels, while with PN it is associated with the Calcium and sodium channels.

I really haven't yet got my head around all the autoimmunity stuff and what it all means - just find the relationship between BFS and PN kind of interesting.


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