[LouLou1978]

Hi there,

I understand there has been a few clinical trials on the above drug which i believe has been successful in Sarcoidosis and Diabetes. Does anybody think this will be used for a more broader range of neuropathy in the future?

Loulou

[mrsD]

Here is an article about it:
http://www.prnewswire.com/news-relea...280635872.html

If it retains its designation for sarcoidosis associated PN...others would not be likely to afford it as insurances would require a diagnosis for sarcoid.

This happens here with Lidoderm (lidocaine) patches which only have FDA approval for post herpetic neuralgia.

As a peptide it looks like it will be injectable. It might get clearance in about 3-5 yrs. It may however open doors for PN treatments also in the future.

Thanks for posting this.

[LouLou1978]

Thank you Mrs D, i am hoping it will open doors for other neuropathy sufferers, i believe it also states it is disease modyfying , unless i have got this wrong, i am all new to this.

[canagirl]

3-5 years? ugh... I want it now (as I'm sure everybody else does). when are clinical trials? With clinical trials must you have one of the diseases specified? IF you are idiopathic are you out of luck?

[canagirl]

sorry, one more question. I see this drug is for diabetic or sarcoidoisis neuropathy. does that mean it won't work on other types of neuropathy? Wouldn't trials want to be done on many different types of neuropathy? Why only those two? Sorry, I don't understand much about this stuff

[canagirl]

This drug is being tried in the US. Does anybody know how drugs come to Canada? In general, if drugs are approved in the US are they approved in Canada around the same time? Or does it take years for to see it in Canada?

[Enna70]

Originally Posted by canagirl

sorry, one more question. I see this drug is for diabetic or sarcoidoisis neuropathy. does that mean it won't work on other types of neuropathy? Wouldn't trials want to be done on many different types of neuropathy?

some people do very well on Lyrica and that's for diabetic neuropathy....we all respond very differently to the medications out there....so sadly it's a hit or miss kinda of thing....

[madisongrrl]

Originally Posted by canagirl

3-5 years? ugh... I want it now (as I'm sure everybody else does). when are clinical trials? With clinical trials must you have one of the diseases specified? IF you are idiopathic are you out of luck?

For the clinical trials there is a very exact inclusion/exclusion criteria. It depends on what indications they are looking to have on the final label. Phase 3 trials test the drug on individuals that have the disease that they are looking to treat.

[madisongrrl]

Originally Posted by canagirl

sorry, one more question. I see this drug is for diabetic or sarcoidoisis neuropathy. does that mean it won't work on other types of neuropathy? Wouldn't trials want to be done on many different types of neuropathy? Why only those two? Sorry, I don't understand much about this stuff

Drugs can't be made so narrowly as to treat diseases in a precise way. There won't know this until there is more data. It depends on the mechanism of the drug as well.

[beatle]

It would be used off label if positive results were seen with other neuropathies.