[LouLou1978]

Hi all,

I have been on here a few times, I have SFN full body. I am in UK and have just had a letter my neurologist sent to my GP read out in full. These include comments on what the skin biopsy showed. My skin biopsy results came in January but my neurologist works in another country for a few months so was away and has only just commented on it.

my skin biopsy results were a bit unusual, it showed an increase in the nerve fibers rather than a loss. My neurologist has said this is consistent with inflammation. it was suggested by the professor I saw in London that it could be neuroinflammation or possibly caused by the drug Metronidazole. My neurologist thinks its not the Metronidazole as I would have had to take it for a long time before it causes these changes. I am lucky as he actually specialises in PN, so is quite clued up on SFN.

I now have an appointment to discuss steroids and IVig, It was advised in the letter this is something which shouldn't be taken lightly. He advised with IVig I would have to go to day clinic, for 5 days to have the treatment. I am also confused as how I understand it has to go to a panel in the UK, I am sure this is correct as i have checked out the criteria online, SFN isn't on the list!. There has been no mention of this in the letter, only that it will be given on a trial period. It maybe because the skin biopsy showed inflammation I don't know, but I am keen to get my appointment earlier so I can find out.

I just wondered, so how I understand, if there is inflammation going on , will this help? I really hope so, I was hoping it was the Metronidazole so then I guess it wouldn't get worse, now the neuro says it isn't, there is no chance of getter better or the nerves repairing.

I would be grateful of any comments :-)