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Yes--
--taking gabapentin or pregabalin will get the kidneys working harder. The fluid retention side effect seems, at least anecdotally, to happen more often in those with lessened kidney function. DEFINITELY intake fluids when on these drugs, and move around to tolerance to promote fluid elimination.
As to whether these meds have an effect on metabolism, many of the central nervous system anti-epileptics, with the exception of Topomax, seem, again anecdotally, to have some "slowing" effect in some people. But I don't think there are any double blinded well controlled studies out there (at least that I'm aware of) comparing basal metabolic rate and thyroid function for people taking doses of these versus those not. |
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Fluid retention
I definitely had fluid retention with the Gabapentin. My feet swelled so much that I have black and blue marks under my toenails. I was taking 500 mg of Naproxen with that also and I quit taking that. I am starting to notice the swelling with Lyrica now too. My Pain Management doctor told me to get a diuretic from my GP but I really don't want to take that too. I have been trying to walk more. I walk my dogs now for about 45 minutes to an hour a day and also try to go for a walk by myself when the pain allows me to.
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how much gabapentin were u taking? |
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