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-   -   Neuro confused...I have no answers! (https://www.neurotalk.org/peripheral-neuropathy/226651-neuro-confused-answers.html)

zkrp01 09-29-2015 06:30 PM

Impingement-Trauma
 
Quote:

Originally Posted by carrieLharris (Post 1174377)
Unfortunatly, I am only getting worse.

B12 was 351 but she didn't seem too concerned with that result.
What about MRI of lower back? That wasn't ordered and I was wondering if that would be beneficial?

Thanks for the dr. info at KU!

Two things to check for with MRI. I had nothing wrong until car accident, hard shock up right side. I lied, I was a poor diabetic patient playing games w/Dr. then had car wreck. Trauma induced Neuropathy is a real thing. Good Luck, Ken in Texas.

carrieLharris 09-29-2015 06:34 PM

I bought the B12 but haven't taken much. Didn't think it would make much difference.
I will start tomorrow morning! thank you so much!

zkrp01 09-29-2015 06:44 PM

300's is low
 
Quote:

Originally Posted by February (Post 1174393)
Your B12 is toooo low!

I was in the 300's too. My doctors weren't concern either. So I wasn't either. That's why neurotalk is so important. You will learn how important taking a methyl B12 on an empty stomach every morning until your levels reach over 1000. Metaformin drains it from you. I took mega doses when I learned how bad low levels can be. I felt improvement right away. I'm sure I can walk on my heels again because of it.

I was given an mri of my back as part of the workup.

but may not be bad enough to be symptomatic. Mine was 119 at one point and didn't have symptoms until I had a small car crash. I believe that Metformin taken over time can block b-12 absorbtion in a certain percentage of people. I am thinking one-third. So in my book that means if you take Metformin you need to know what that number is. I took shots monthly plus pills and felt improvement over the course of 5 or 6 mo. Good Luck, Ken in Texas.

February 09-30-2015 11:36 AM

Quote:

Originally Posted by zkrp01 (Post 1174426)
but may not be bad enough to be symptomatic. Mine was 119 at one point and didn't have symptoms until I had a small car crash. I believe that Metformin taken over time can block b-12 absorbtion in a certain percentage of people. I am thinking one-third. So in my book that means if you take Metformin you need to know what that number is. I took shots monthly plus pills and felt improvement over the course of 5 or 6 mo. Good Luck, Ken in Texas.

I question the diagnostics. I've read that everyone in the 300's should be tested for pernicious anemia. I asked the hematologists about it. He did nothing. I regretfully didn't pursue it. I even developed vitiligo while taking b12. The vitiligo stopped when I started the methyl b12. It's so painfully obvious now. I'm with you about monitoring. I don't trust the results of conventional tests after my experience.

glenntaj 10-01-2015 06:19 AM

Personally--
 
--I think anything up to about 500-550 is suspect--at least if one is eating a diet with animal protein sources in it (vegetarians/vegans are very often affected by lowering B12 levels as they do not get it from diet and we cannot manufacture it ourselves; such people should definitely supplement).

There have been people who have been symptomatic of B12 deficiency even into the 600 range.

I suspect that the original normal ranges for B12 are set too low at that end. Japanese labs, due to the drug-induced B12 crisis that Mrs. D has talked about here, tend to set the low end of their lab ranges around 500-550, and many have no upper limit. (I also think the upper limit of some labs in the 900 range are a little ridiculous--if one absorbs B12 well on a non-vegetarian diet, or if one supplements, especially with a daily B-complex, one's readings are likely to be higher. My wife takes a daily B-complex with 125mcg of B12 in it and her levels are usually in the 1100's. I take methylcobalamin 1000mcg three times/week and get readings in the 1500's-1800's. This, of course, frightens uniformed doctors unless you explain it to them--if they're willing to listen.)

Neuroproblem 10-02-2015 04:01 AM

Quote:

Originally Posted by glenntaj (Post 1174758)
--I think anything up to about 500-550 is suspect--at least if one is eating a diet with animal protein sources in it (vegetarians/vegans are very often affected by lowering B12 levels as they do not get it from diet and we cannot manufacture it ourselves; such people should definitely supplement).

There have been people who have been symptomatic of B12 deficiency even into the 600 range.

I suspect that the original normal ranges for B12 are set too low at that end. Japanese labs, due to the drug-induced B12 crisis that Mrs. D has talked about here, tend to set the low end of their lab ranges around 500-550, and many have no upper limit. (I also think the upper limit of some labs in the 900 range are a little ridiculous--if one absorbs B12 well on a non-vegetarian diet, or if one supplements, especially with a daily B-complex, one's readings are likely to be higher. My wife takes a daily B-complex with 125mcg of B12 in it and her levels are usually in the 1100's. I take methylcobalamin 1000mcg three times/week and get readings in the 1500's-1800's. This, of course, frightens uniformed doctors unless you explain it to them--if they're willing to listen.)

getting to 600, means you could be suffering from b12 toxicity, which can cause pn like symptoms. b12 is a complicated molecule and bacteria produces it

mrsD 10-02-2015 08:18 AM

Quote:

Originally Posted by Neuroproblem (Post 1174963)
getting to 600, means you could be suffering from b12 toxicity, which can cause pn like symptoms. b12 is a complicated molecule and bacteria produces it

Neuroproblem---- could you please explain this post? Provide links if you can too.

At this time there is no upper limit to B12 levels, established by research.


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