I am reminded of a study I read a while back about Charcot Marie Tooth. (a form of hereditary neuropathy)

The study was about fluoroquinolones triggering a CMT postive patient who was in late middle age, and had no symptoms of CMT until taking Levaquin for an infection. This activated the CMT and he now has active neuropathy. So just having the genes, didn't result in an active disease process until the drug came along.

Janieg, I am glad that you have found out that you have two copies of the rs4977574 G allele.

The paper that you cited is a nice example of how dietary changes can mitigate the effects of a genetic risk factor.

I think one of the ideas behind DNA banking, which is really blood sample banking, is that at some FUTURE date there 'may be' very much more sophisticated tests for genetic markers AND sophisticated treatments for undesirable genetic conditions.

I always think how amazed a 'visitor' from 1800 would be to witness hip replacements, open heart surgery, or just to understand the power of antibiotics.

Hugs, ElaineD