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Has anybody heard anything about 'atexakin alfa' neuropathy treatment in development.

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Old 11-20-2015, 08:27 AM #1
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Default Has anybody heard anything about 'atexakin alfa' neuropathy treatment in development.
A few months ago a promising treatment was said to be in development. I haven't heard much on it since then, has anyone? Maybe something to bring to our neurologists and ask...

http://www.pharmaceutical-technology...atment-4665940
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Old 11-20-2015, 09:04 AM #2
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This is very interesting. However, I cannot find anything about it at the FDA or Orange Book. I suspect they will have a while yet to do that legal paperwork and perhaps trials.
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Old 11-21-2015, 02:10 AM #3
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Just reading between the lines of the article it is likely that an IND has been filed and no holds have been placed by the FDA - especially if Merck Sorono has formed a partnership with this biotech company. It's not in the FDA Orange book because these in-licensing agreements tend to happen during the Phase II clinical trial stage. I'll try to check on this at work, but I would imagine it will be a while before we see Phase III results.
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Old 12-02-2015, 12:10 PM #4
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Quote:
Originally Posted by madisongrrl View Post
Just reading between the lines of the article it is likely that an IND has been filed and no holds have been placed by the FDA - especially if Merck Sorono has formed a partnership with this biotech company. It's not in the FDA Orange book because these in-licensing agreements tend to happen during the Phase II clinical trial stage. I'll try to check on this at work, but I would imagine it will be a while before we see Phase III results.
I am sure if it was a cholesterol related drug they would express the approval of this.
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• R-Lipoic Acid: 100mg - 300mg Daily
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• Grape Seed Extract 200mg Daily
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Old 12-02-2015, 12:52 PM #5
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I am sure if it was a cholesterol related drug they would express the approval of this.
Yes, I looked into this a little bit - it's not being fast-tracked. I can't find a ton of info on it, but I did look at some of the animal studies on PubMed.

http://neurotalk.psychcentral.com/sh...12#post1186212
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Old 12-05-2015, 05:16 PM #6
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So did anybody find something in clinicaltrail.gov?This would be interesting to follow.

But i agree this is very interesting so there are now 2 drugs being developt

I also cant find the website from "Relief Therapeutics"

A explenation of what phases in clinical trails mean

http://biopharma.merckgroup.com/en/r...al_trials.html

European clinical trails
https://www.clinicaltrialsregister.e...opathy&page=19
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Old 12-05-2015, 11:24 PM #7
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Phase 1 trials don't have to be reported for drugs or biologists on clinicaltrials.gov, so there won't be anything posted yet. (FDAAA801)
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Old 12-06-2015, 06:05 AM #8
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I have big a little bit deeper this is what i found til now

http://www.businesswire.com/news/hom...-Commercialize

In the above article interleukin-6 is mentioned so here you find what this stuff is all about
http://www.news-medical.net/health/W...rleukin-6.aspx

Relief Therapeutics looks like a one man company.. lead by Dr. Gael Hédou his telephone number and email adress are mention in the top article

But here is the linkedin adress
https://www.linkedin.com/pulse/relie...?trk=prof-post
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