Hi Mrs.D and Melody

Your earlier posts and replies are very helpful and inspiring for me.

I need your advice/help to understand what exactly is happening to me, I have neurological symptoms.

About me :
I have drinking history of last 8 months (twice in a week) from April, 15 to Nov,15 and then 1 month daily drinking till 23rd Dec, 15.
I have been drinking Whisky and sometimes Rum. whisky brands glenlivet, Glenfiddich : 120 to 180 ml daily in evening followed by dinner.
Smoking : 6 - 10 ciggrattes daily

Problem started on :
On 23rd Dec, 2015 : Met with minor accident after binging drinking, had whiplash and minor bruises on hand.
On 24th Dec, 2015 : Decided not to drink anymore and not to smoke anymore. but didn't had any neck pain after that whiplash.
at 2.30 pm in night while i started to sleep, suddenly all my body started inner shaking or vibrating, feeling like seizures.
I could not sleep whole night and next day on wards i started feeling numbness and tingling in my left arm.
Also one thing i remember, while seizures were coming it made me to fart without much control on it.

I got admitted in florida hospital, Carrolwood - on 25th Dec, 2015
Doctor did CT scan of head and took some heart pictures along with few blood tests,
everything was normal including pulse and blood pressure.
They gave me IV through injection however. and from next day Diarrhea and yellow dark urine started with urine burning sensation.

Symptoms from 26th Dec to 15th Jan, 2016
1. Loss of appetite
2. mental tiredness, body weakness, weight loss (drop from 155 to 150 lbs)
3. can not eat spicy or oily or meat, cause diarrhea or constipation, now i am eating less spicy food and it is going ok now a days.
4. dry mouth (specially in night)
5. dehydration (specially in night)
6. Pain in neck while sleeping on one side, however i can sleep on back with less pain
7. Pain in mid back while sitting straight
8. Feeling mild vibration or shakiness in legs or body while sleeping, its not consistent however.
9. numbness in fingers
Left hand - first finger
Left hand/right hand - pinky finger feeling cold always

Symptoms From 15th Jan
2. mental tiredness, body weakness - comes and goes now a days.
3. can not eat spicy or oily or meat, cause diarrhea or constipation, now i am eating less spicy food and it is going ok now a days.
4. dry mouth (specially in night)
6. Feeling mild inner vibration or shakiness while sleeping on left side, however i can sleep on back with less pain
8. Body shakes along with increased heart rate as well.
9. numbness in fingers - These symptoms have been reduced
10. Left hand immense pain : right from lower head or neck to left hand wrist including left shoulder, triceps and elbow are starts paining in day time.

About Xray MRI and blood reports,
Doctor said, I have B12 deficiency and Vit D Insufficiency
However, CT Scan, Xray of back spine and Mri of Cervical come negative. except some existing stenosis.
report on 12/31/15 : Serum panel Vit b12 241 pg/ml
report on 2/03/16 : Vitamin D,25-OH, TOTAL,IA - 24L (Normal range states as 30 - 100ng/mL)


As solution, I am Taking daiiy below vitamins
B12 vitamins 1000mcg Cyano form - brand : Natures bounty [ From 4th Jan 16] : after breakfast in morning. after ceral and tea.
D3 - 4000 IU - brand : Natures bounty [ From 3th Feb 16] : after breakfast in morning. after ceral and tea.

Symptoms Today
12th Feb, 2015
all above symptoms are reduced to just below points
1. Left hand still innerly tremble and numbess, it is also spreading in other parts of body like left lag and right hand along with heart race.
I also feel upper/mid back muscle crawaling while sleeping.
2. Dry mouth in night ( usually i will have constipation in next morning and more body inner vibrations in night )
3. Constipation 2 times in a week. (after eating wheat product in night)

Doctors are saying you may be having alcohol withdrawal symptoms, but no one is giving me medicines which can heal this problem.
1. Please let me know if i should change the vitamins suppliments types or brands or i should take other vitamins too ?
Should i take heavy doses of vitamins ? Injections ?
2. Will neurological issues will be permanent problem for whole my life ?
3. Along with Withdrawal or B12 deficiency i also have anxiety about my health for sudden death or paralysis while sleeping, which really want to control.

Please help me. I DON'T WANT TO DIE !!!

*
Weight 148 lbs, Height 5.8"

Hi deepak2016

Other NT members will be far more able than I am to offer you thoughts about your neurological signs than I am.

However, as far as your drinking is concerned (I am in remission from alcohol abuse), standard advice is that men should drink no more than 21 units of alcohol per week, no more than four units in any one day, and have at least two alcohol-free days a week. Women should drink no more than 14 units of alcohol per week, no more than three units in any one day, and have at least two alcohol-free days a week.

One unit of alcohol is about 35 mL of 40% v/v spirits.

People who drink can be deficient in thiamine (Vitamin B1) - this deficiency can lead to neurological signs. This is discussed in this link, which includes a list of foods which are rich in it; https://ods.od.nih.gov/factsheets/Th...hProfessional/.

Taking thiamine as a supplement is another option though I would be inclined to discuss this with your health care team.

All the best.

[B12 vitamins 1000mcg Cyano form - brand : Natures bounty [ From 4th Jan 16] : after breakfast in morning. after ceral and tea.]

Did you find the B12 details in the sticky thread?
*Best if taken with an empty stomach & methylcobalamin form*
Many take it first thing in the morning.

Thanks Kiwi for your suggestion on thiamine.

I forgot to mention that i also take below vitamin
B-Complex with biotin - 1 pill daily after dinner.

which contains (Thiamin - 25mg)



Guys please advice me.. :-)

Is B12 Vitamin report of 241 pg/ml can cause neurological symptoms ?

Deepak2016, 25 mg/day thiamine is well above the RDA, which is about 1 mg/day. It seems that an intake of a lot of thiamine is probably safe - probably it is not absorbed well at intake levels above about 5 mg/day - the excess is just excreted. Because of this a Tolerable Upper Intake Level (UL) has not been set for it though that does not rule out the possibility that it could have adverse effects in some people (taken from the link that I posted above).

Biotin deficiency is very rare (people whose diet is adequate get enough from their food) but taking a pill containing it will probably not harm you.

The quick answer to your question is, YES. A level that low can cause neurological symptoms. The NEW recommended minimum level is 400 and those WITH neuro symptoms, should be keeping their level much higher than the minimum. That being said though, MrsD is the resident expert on Vit B12, (level, cyano vs methyl, how much to take, when to take, best brands, etc). She's also very knowledgeable about Vit D. I'm sure she'll comment when she sees your posts.

Yes, Deepak, your B12 level is low by today's standards.

400pg/ml is now the cut off for beginning supplements.

You can get low, from autoimmune issues, from using certain drugs like stomach acid reducers or metformin, from following a vegan lifestyle, or from inheritance of certain genetic flaws. (MTHFR) which is a failure to methylate B12 and folic acid.

This is why methylcobalamin is best to use, since you do not know if you are one of the 10-30% who have this mutation.

You need to take the B12 on an empty stomach with no food for about an hour after.

Dark urine is a sign of liver problems, so make sure you had liver tests for alcohol damage, and for the major hepatitis viruses.

You are the captain of your own body. Choose to treat it well by stopping smoking and avoiding alcohol and recreational drugs. Feed it healthy whole foods, and get good sleep. That is what it wants.

Doctors are saying you may be having alcohol withdrawal symptoms, but no one is giving me medicines which can heal this problem.
1. Please let me know if i should change the vitamins suppliments types or brands or i should take other vitamins too ?
Should i take heavy doses of vitamins ? Injections ?
2. Will neurological issues will be permanent problem for whole my life ?
3. Along with Withdrawal or B12 deficiency i also have anxiety about my health for sudden death or paralysis while sleeping, which really want to control.

Please help me. I DON'T WANT TO DIE !!!

I had a low b-12 level and got into a car wreck also. After 4 days I went to ER with a burning pathway from hip to knee. Couldn't sleep and inner quaking. Started only right side but went to left side after 60 days. My b-12 wass 119 and started supplements (Methyl) plus injections, stayed with both until my number got to 900+, then stopped injections. Injections were once a month. I went down for about 18 months and bottomed out using a walker and taking pain meds daily. Since that time I no longer use the walker and take no pain or sleeping pills any more. It may take a long time to travel this road so you have to fight the panic and not worry about death or paralysis. I was absolutely convinced I was headed for a wheelchair for a long time. In my opinion, you have to say goodbye to alcohol, it wants to take you the wrong direction. If you search here for Alcohol Induced Neuropathy you can read other stories and maybe get a few pointers about getting sober. You are going to have to take better care of your body now. Good Luck, Ken in Texas.

Deepak:

I don't take stomach acid reducers and i used to eat meat a lot.
However if we talk about genetic flaws - Yes my mother and grand mother both had indigestion, bloating issues. but not any neurological issues signs.
In fact my all (2) brothers continuous have stomach related issues and also no neurological issues signs.

Things i would like to mention is,
I have a birth defect 'spina bifida' at spine level C7 - T1.
My Folate Serun on 12/31 was : 22.1 ng/mL

Question 1. what tests i should suggest my Doctor to see if i have any kind of Autoimmune issues, MTHFR ?

Deepak: Yes today i will visit CVS for B12 myethyl form for 1000 mcg (daily one dose, empty stomach, one hour gap)

Deepak: I already have done below tests and they all cames negative
1. HSV-1 and HSV-2 and Chlamydia
2. HIV
3. HEPATITIS A, B, C
4. Complete stool test
- Here they had found few Blastocystis species - they have given me probitics for this

Deepak : I have completely stopped drinking and smoking on 23rd Dec, 2015. I never took any kinds of drugs.
Thanks Mrs. D for your reply, i will have health whole food and good sleep. Thanks :-)