I'll try to make this short, but a friend with knee pain from OA is working with about 8grams ascorbic acid and in about 4 days she's telling me, she feels like she has new knees. I'm on this protocol now. She is taking 4grams twice a day, using NutriBiotic pure Vit C. She takes powder form...I have to get some.

I've read a LOT of Linus Pauling info in the last couple days and Pauling came up with 6grams daily is what would help to keep us healthier. I have been taking most days 2grams.... Pauling it's said took 12grams daily. He's been gone since 1994 and died at 93. But his life with Vit C lives on. He also said that if everyone took at least 500mg Vit C daily, many lives would be saved.

I have a great link from Mercola on Pauling and may post it soon.

Anyway, I've done a little search on Vit C and nerve pain issues. Info is out there. Foods are great if one believes they can get adequate support, I don't believe I can and I eat pretty well. But how much can we eat?

Taking higher Vit C one has to be aware that C can cause more acidic body so taking a little baking soda with the C is important or a little bit of calcium to keep us alkaline enough.

Anyway, I'm on my 2nd day of higher Vit C for arthritic knees and OA in general and keeping the faith this will reduce pain...Vit C builds collagen and attacks free radicals.

One friend reminded me to make sure I'm taking probiotics, which I am. A 30billion unit Healthy Origins product.

Higher doses of Vit C can cause loose bowels, so be on top of that one.

Just sharing what is my NEW endeavor. C

This is interesting. I very much wish there was funding for serious studies into vitamin and mineral use to treat all sorts of health conditions. We have so much naturally at our disposal, but for the sake of profits we don't explore them in any sustained and serious way. Very sad.

David, it's a pharma world and we have to try things to heal ourselves..hear from other people's and friends' experiences and go from there. Big funding isn't going to happen for supplements...there is some funding done by the mfgrs but that's about it. Pauling has a long history and even won Nobel prize(s). To this day the FDA will not approve IV Vit C in cancer treatments. The longer one lives, the more one sees what goes on if eyes are open.

Yes, indeed, word of mouth, etc. can and is useful to us, though it would be very good to have more precise and science based research. It would only help and take such natural therapies to new levels of precision and utility. But we all know why that won't ever happen in any substantial way. More a dream than anything else.

David, I hear you and for me, the science is my body and how I'm doing. I know what has caused my issues and seek out all I can to manage and not do more damage. We are in control and can't go back and work on today and as best we can for the future. Thank goodness for the "net" and all the wealth of info we can consider. Before the net I bought books and used my healing books. I didn't get on the net until 2005...so late I'm sure considering MOST here.

"To this day the FDA will not approve IV Vit C in cancer treatments."

Possibly the reason for this is that there is no convincing recent evidence that Vitamin C is of any use in treating cancer.

This free-access systemic review is worth a read in this context; http://www.ncbi.nlm.nih.gov/pubmed/25601965.

That review is not very informative.
No mention of how much Vit C was used or how often.
That was the first thing I was curious about when reading it.

Jo*mar, the doses varied a lot (between 1 and 10 g/day when Vitamin C was taken by mouth and between 500 mg i.v. daily to 100 g i.v. three times per week).

What the systematic review seems to have shown is that there is not yet any strong evidence that Vitamin C can help, regardless of dose, dose frequency or mode of administration.

More studies could very easily change this.

Vitamin C in high doses can have some bad side effects. I would be a bit wary at this point. There are limited studies if any at all that really show it specifically helping neuropathy.

High doses of vitamin C have been associated with multiple adverse effects. These include blood clotting, death (heart-related), kidney stones, pro-oxidant effects, problems with the digestive system, and red blood cell destruction. In cases of toxicity due to massive ingestions of vitamin C, forced fluids, and diuresis may be beneficial.

Hi Friends, we can't forget the other side of the issue of medicine. I've read articles of up to 100K die from interactions annually. That was a few yrs ago, don't know about today's figures.

http://www.npr.org/2011/09/27/140849...ler-in-the-u-s