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--that I hadn't already listed in private email; chief among them is that the titer is so high comparatively that it might be a lab error and the test is definitely worth running again.

Many of us have experienced lab errors in the past. Way back in the more acute phase of my neuropathy I had a test for islet cell antibodies come up positive with a pretty high level--speaking of Type I diabetes--in a series of tests in which there was no other evidence of it. So we ran it again over the next three weeks--twice--and it was negative both times. And it's never been positive since (I have it run every few years).

One thing that was interesting about that time is that the test result was delayed several days beyond the time for the other test results. I sometimes wonder if that kind of situation reflects a lab misplacing or otherwise goofing up a sample . . .

(BTW, just has my annual basic blood work done--very good, and I am particularly proud that I've gotten my hemoglobin A1c back down to 5.5 from 5.9. Type II diabetes does run in my family and it will be a lifelong struggle to keep those glucose levels low. Diet and weightlifting--building muscle, which is less insulin resistant than many other types of body tissue--seem to work at least somewhat for me.)

Quote:

Originally Posted by LizaJane (Post 1214328)

Hi All,

Some of you may be old-timers who know me, but I've not been on the forum in ages, so I may be a new face to most of you.

I had idiopathic sensory and autonomic neuropathy for years before I was diagnosed with Lyme, and did great with treatment. I made up the lizajane.org charts that people use to help navigate through diagnosis for neuropathy and Lyme.

Lately, I've had issues: fatigue, a finicky leg, odd stuff. But odd stuff has been my history, and nothing lasts and I generally end up doing ok.

Because of my recent odd stuff--when I get tired, my foot gets floppy--my neuro ordered some new tests, and the GAD65 came back very abnormal.

Can this not be awful news? Anybody here understand this auto-antibody enough to tell me something reassuring?

I do get IVIG, and I'm hoping that somebody whose antibodies were in the IVIG had this, and not me.

LizaJane

4554

Hi Liza,
So nice to hear from you!! I am sorry I do not know anything about Gad65, but I just wanted to chime in and say hello again.:)

PS. When I had lumbar surgery(discectomy) in 2010, the sciatic nerve was beaten up a bit the surgeon told me. When I get very tired my leg goes a tiny bit wobbly.