Kiwi I've read this link and found it very interesting. I believe methotrexate has been used to treat people with OA to good effect over the past few years so this makes sense of the inflammatory overlap.

Re the role played by compliment in autoimmunity - I did just want to ask if you know what the significance of my raised C3 and C4 might be? I asked a GP who said probably my severe yeast infection but I'm not convinced. I know that these compliments are usually significantly low rather than high with Lupus but have got no further with my research into raised compliment levels. Could it relate to OA do you know?