I use a chart to check for any signs of vision changes...yes, this is done at home.

As MrsD has said, Plaquenil is one of the least toxic for rheumatologic drugs...but as with any drug, it comes with side-effects. I, personally, have experienced no side-effects from it...and know many others who have not. But of course, there are those that cannot take it due to GI upset (most common) or other reasons. There is no such thing as a risk-free treatment...especially when it comes to treating rheumatological conditions. You just have to weigh the pros/cons and risks vs benefits.

You are doing the right thing...gathering information to make an informed decision. The decision you make can always change. You can stop taking it if you have any negative side-effects (without permanent harm), or if you choose not to take it now, you can decide to try it down the road.