Hello all, I've finally gotten all of my blood work back and it has been evaluated by my neuro. All of the test were unremarkable except 3 test. My C-Reactive Protein is 3.1. This is severe inflammation according to my doctors words. Vitamin B6 is 87.3. The normal high is 32.8.y vitamin B12 is 1642. The high side of normal is 816. The neuro didn't say anything about my vitamin levels. Due to new symptoms that have developed over the past 3 - 4 weeks, my neuro has scheduled me for an MRI of my brain. I have it on the 12th. I've complained so much on this forum and I appreciate your help. Maybe I'll find something out soon. Take care of yourselves. God bless, KATO

Hi Kato,

It's always hard to know if it's better getting an explanation or not! I'm sorry you're still searching and hope your MRI goes well.

I just wanted to jump in with a link to B6 toxicity since it can affect nerves and cause GI symptoms. If you're taking any B vitamins you might ask your doctor about stopping those for a bit.

Can Too Much Vitamin B Cause Problems? - Ask Dr. Weil
Vitamin B6 (pyridoxine) Safety - Mayo Clinic

Take care. I hope you find relief and answers soon,

Did you stop taking the B12 for several days before the blood
tests? If not, the blood work is not accurate.

KATO, it might be worth getting your CRP level re-tested in a month or so.

Generally, elevated CRP can occur in two situations. The first is a short-term response to an acute infection - once the infection is over CRP levels go back to normal.

The second reason for elevated CRP reflects chronic conditions, including atherosclerosis, SLE, vasculitis, rheumatoid arthritis and inflammatory bowel disease among others.

A re-test should help to distinguish between these possibilities.

Yes I did.

Kiwi33, I have DDD, DJD osteoarthritis and something else going on that causes the CRP to be high most of the time. I have a cardiac workup each year. I have very bad family history of cardiac disease. The lupus also, I forgot that.

There is some evidence that vitamin C can help lower elevated CRP levels. This is not a huge effect, but a beginning. According to this study Vitamin C was similar to statins. And we all know here how awful statins can be for nerves.

Vitamin C treatment reduces elevated C-reactive protein

Paying attention to Vit C intake is also important.

Vitamin C Amount | Vitamin C dosage

He should have mentioned your b6 levels. B6 Toxicity mimics MS and many other disorders. Anything over upper level is b6 Toxicity. It can cause many symptoms, especially anxiety and nervous system complications.

Also, most neuros aren't aware of b6 Toxicity. Here is a site that may give you articles and such. Vitamin B6 Toxicity

KATO-- Since you have had such a life threatening heart problem at a fairly young age, and because your relatives have similar issues, I would get a DNA test for MTHFR. This is mentioned in this good link as connected to high B6 test results as well:

The Cause of Vitamin B6 Toxicity is Not What You Think

The main website for it is here:
MTHFR Mutation | MTHFR Gene Mutation | What is MTHFR? - MTHFR.net

This test does not need a doctor to order it, from 23andme.
If a doctor does order it your insurance may pay for it, because of your cardiac history.

It seems that frequently now, we see a poster here who has done this test and tested positive for one or more mutations affecting methylation. We have one poster here recently (janieg) who found a mutation in biotin metabolism. She is our first one!

I'd really recommend you do this test to see if you and/or your family members could benefit from it.