Too high B6 might not be what you think:

The Cause of Vitamin B6 Toxicity is Not What You Think

The suggestion is to take activated B6 called P5P to help.
People may not convert B6 pyridoxine, to active P5P, for several reasons.
1) genetic failure of pyridoxal kinase in the liver

2) low levels of B2 riboflavin which is a cofactor of pyridoxal kinase,

3) use of certain drugs, including caffeine which block conversion.
Near the end of this paper (starting at page 63), is a list of drugs they found so far that block pyridoxal kinase activity. The list is growing by the year, as more drugs are tested for this effect.
http://scholarscompass.vcu.edu/cgi/v...07&context=etd

Suffice it to say something is preventing activation of B6 to P5P for some people, so they test high as the INactive B6 builds up in the body.