Google Loratadine and search it's side effects. Find out everything you can about it and see if you find a link to your symptoms.

Over my life I have taken a boat load of that stuff among others, so pointing a finger at it for me won't work.

Ugh....:

Loratadine Side Effects in Detail - Drugs.com

Look at nervous symptom......"paresthesia"...never heard of it, but man does it "fit".

Appreciate that although my symptoms started long before I ever took Loratadine or any antihistamines. The problem with Google is you can find seemingly contrary information to claim that other antihistamines (like Benadryl) may provide relief.

OP: I've been off all antihistimes for well over 23 yrs since I found Pycnogenol and then Grape Seed Extract a year later. I love NOT taking those pharma drugs. I've talked a lot about Grape Seed Extract here and why not work with it for your issues... Do a search of all the info on Grape Seed Extract here.

Thanks, I'll definitely try that as I've tried numerous supplments such as Billberry, Lutein, Cinnanon, Chromium, etc. While difficult to pin-point, I'd say I've have the best results with Alpha-Lipoic Acid & GABA. I only use the Amitriptyline as needed when the sensory symptoms are particularly intense.

Hi Mark
Reading your post...i can definitely relate,symptoms are very similar..ive been dealing with this for the past 6 months with no answers..how did iypur symptoms start was it a sudden onset or a gradual one.

It was sudden but a year before I had the full body senory symptoms, I developed a chronic itch on the small of my back and it was diagnosed as Notalgia Paresthetica.

Fortunately or unfortunately, the nerve symptoms (pins, needles, burning, numbness etc), the location of symptoms, and intensity are variable & eposodic. For example, the last few days, the senory symptoms are little noticeable and I don't need any meds but last week the symptoms were bad enough to need the Amitriptyline. The doc tells me that's not typical of PN. Also, while my symptoms tend to be most felt in hands & feet, they can occur anywhere including the scalp and back, and that I had a brain MRI.

Hi Mark I've inboxed you

Interesting stories.
I've similar issues going on the last three months.
I've a history of thyroid issues from 2012 where I got the following symptoms.

1. Burning sensations in legs/feels
2. This itchy feeling in my hands top
3. Numbness hands and feet while sleeping
4. Twitching in muscles (bfs)

Now in 2012 I had flares of hyperthyroidism and hypothyroidism.
I had the same flare in 2013 and 2016. I spoke with 4 endos. They basically aid, we think it's hashimoto but your thyroid looks healthy on the scans so we think it's recidive 3 times. Two endos were professors and both were contradicted.at the end I still don't know what is. I've quite high antibodies.
Fast forward this year. Again weird sensory stuff and all looked hypo. I was like here we go again with this crap.
At the end my thyroid analysis looked normal but noticed my b6 (to high)and vitamin d was to low.
I again got the twitching and freaked out due marketing of a dreaded disease.
Then I checked my history in mails and found that I mailed with my endo.in 2012 and i got the deja vu from it and honestly I calmed down as if I had this in 2012 also I would not be here typing this story is it was the dreaded disease ( I jtn't type the name)

Went to neuro and got cleared and had mri spine and head all good. I did this in Belgrade in a private clinic. Here in Netherlands the neuro didn't see a reason for it. She did a ct scan pure for reassuring but you know how its works. It helps for a couple of days

Now I got the same symptoms as in 2012 but thyroid is "normal". Still high antibodies so autoimmune is there.
I got following symptoms

1. Burning in feet/legs
2. Weird itching in hands and sometimes burning
3. Twitching mostly in legs but honestly total random ( typically widespread which is a good sign. See aboutbfs.com
4. Numbness legs and hands during sleep totally random
4. Cold shivers
5. Paresthesia random but not often

I mostly have this when I sit or ly down on the couch. When I move rarely.
I've read so much about these symptoms and on aboutbfs.com so many people got hit out of the blue with this crap.

I believe my high b6 and thyroid unstablness is cause these sensory issues.
Going to academic hospital in Maastricht soon as they are specialed in Europe for sfn. My neuro told me she doesn't suspect it and that is somatic disorder. I was like yeah whatever.