The way in which cannabinoids, including CBD, work on your endocannabinoid system is complex and not well understood due to a lack of research. This is mostly because of the moronic and politically motivated prohibition in the USA. It has affected the rest of the world and so global research too over the last century. More and more research is being conducting with each passing year, and the 2018 farm bill that passed yesterday made hemp cultivation federally legal. This was a milestone.

There could be a number of reason why you had this experience. A simple answer is that over time you build up tolerance and need to increase your dosage. It also sounds like you're taking a very low dose. I don't know what concentration you're taking, since how many drops you take tells me nothing really, but my guess is the dose you're taking is very low and not an effective dose. We measure CBD oil consumption by mg since concentrations vary. An effective adult dose can be hundreds of mg.

Another possible reason you experienced nothing the second time around is more complex and has to do with your endocannabinoid system and the state it is in. CBD and other cannabinoids interact with your body, including your immune system, in complex ways and there could be many reasons why a given dose is effective one time and not another (e.g., degree of inflammation is a significant one). So it's complex unfortunately and there's no easy answer. I know it can be frustrating and confusing but the only thing I can say is it might be worth experimenting to see what works for you.

I know, it's all so expensive. But yes, like any medicine it only lasts so long and needs to be re-administered. You can try the salve from Fully Activated if you like. It works well for many people including myself, but any full spectrum CBD salve should help as long as it's from a trustworthy company. Fully Activated is one such company. I can't speak to any other US companies since I haven't used any others from the states. It's worth a try for sure.

If price is an issue, you can always try CBD isolate and then make your own tinctures. It's not as effective for some people because it lacks the so called entourage effect, but it can be really cheap, as little as $20 a gram. Cannabis prices are too high right now and many CBD companies are price gouging. But there are some good options out there. If you're in a legal state, you can grow your own too. :)

What those criminal American insurance companies will do is as much a mystery to me as it is to you!



[I][/I]

David - You mentioned in an early port that you have done a number of programs over the years with 80% success. Can you please share these programs and which ones yielded the best results?

Thanks

CBD for PN
 

I have used CBD from hemp and from marijuana with zero benefit. Tried different brands and dosages, all to no avail. Unfortunately, there is no independent research about CBD usage, dosage, etc. Here in Nevada CBD and THC have been legal for years and is somewhat regulated for cleanliness and purity, but that does not mean it works. It has become a rip-off industry. Here is a good example: I have tried high dose CBD (1,000 mg/ dropper to no avail). A friend thought he would help me by buying CBD. The product he purchased states clearly:
3mg CBD/dropper!!!. I believe that the business success of the CBD industry tells
us there is an enormous amount of pain in the country that we will try anything. And the prices are outrageous.

I'm sorry CBD hasn't worked for you and there are certainly shady dealers out there as with anything that involves health+money. But this doesn't mean it doesn't work for everyone. In fact, many, most, experience some relief and the limited studies show this when it comes to cannabis as a whole and specific cannabinoids including CBD. I know 2 people myself that didn't find it helped and who were disappointed, but a few dozen more who did. Often CBD combined with THC and other cannabinoids can be more helpful, but again it varies from individual to individual.

The 3mg per dropper is a joke though! Studies show we need far higher doses for it to actually be effective especially for chronic pain. The prices are horrible too, agreed. But there are good companies with low markups and discounts for low income people suffering. Lazarus Naturals is one example. They have a special discount program for those who can't afford it but need it.

In the end, each person can make up their own mind and see if it's worth trying. For me, it helps in a number of ways and I'm grateful for that. We have so few options left to us and really none when it comes to conventional medicine, or none that are not detrimental to our health in other ways, so it made sense to me to give it try.

Hi. I have just applied for the discount on Lazarus Naturals. I attached a letter from Alan's doctor about his severe neuropathy. I also sent them a message explaining about Alan. Lets hope this works.

Alan has enjoyed great results from the cbd oil that we get from around the corner in a Vape Store. My last purchase was for the little bottle of 1000. I give him 12 drops under the tongue. Seems to do the trick but on an especially bad night I give him a bit more a few hours later.

I'm not sure about the dosing or the strength I should be buying. On the Lazarus naturals website, what should I buy? And how many drops? I know everyone is different but this is still confusing to me.

Thanks so much if you can clear this up a bit for me. Alan really could use some help because this poor man falls and has many disabilities.

Thanks so much, Melody

David:

I want to thank you personally for suggesting Lazarus Naturals. Alan was accepted to their discount program. All I had to do was upload a letter from his doctor attesting to his diagnosis of Neuropathy (he's had it for 35 years).

I received their approval first thing this morning. I went to their site and purchased the balm and the tincture of CBD. All for a very reasonable amount. Much less than what I would pay around the corner at the Vape shop. omg. much less.

So I shall update on how he does.

Sincerely, Melody

Hi Melody,

I'm glad it worked out for you and Alan. I hope CBD continues to help him. Topicals and tincture are a great combination and it's wonderful that Lazarus accepted your application.

I would recommend keeping a journal of what dose you use. Begin with a low dose and slowly increase it, keeping a record of how many mg (not how many drops) you give him. This way you can find what they call the lowest effective dose. You may need to adjust and increase the dose depending on the severity of his symptoms and if he builds up tolerance which happens. But this way you can get a good idea what he needs.

I always buy the strongest concentration I can find because it's the cheapest per mg. You can then estimate how many mg you want to give him using the dropper. The concentration and number of drops has nothing to do with the proper dosage and you can plan accordingly.

Hi. What do you mean the number of drops have nothing to do with the dosage? How do I know what I''m giving him.. I do not understand this at all. I am so new to this cbd thing I can't tell you. When I give him the cbd oil, I use a dropperfull. I do not know how much cbd this is.

I am using the 1000 bottle now (that I bought from around the corner). When I get the shipment from Larazus naturals (I bought the high potency 750 bottle), do I give him the same dropperful?

Please help me. I don't know low dosages from high dosages.

Thanks much. Melody

There are different concentrations. First ask yourself how many ml of oil the CBD is mixed into. If you have a 30ml bottle with 1000mg of CBD in it, 1ml will have 33mg of CBD in it. A full dropper typically is 1ml with room for 20 drops, meaning each drop is .05ml with 1.65mg of CBD. The same size bottle containing 30ml of oil with 750mg of CBD mixed into it will have a different dose of CBD in a full dropper and in each drop. So you don't want to be counting how much you give him based on droppers or drops but mg. 750mg of CBD in a 30ml bottle of oil will only have 25mg per full dropper and 1.25mg of CBD per drop.

Edit: To be very clear, you need to divide the mg of CBD in the bottle by the ml of oil (e.g., 1000mg divided by 30 ml = 33.33mg in each ml of oil). Remember a full dropper is approximately 1ml and has approximately 20 drops.

I wish I had paid attention in school in math. I'm doomed. But I'll survive. Let's hope Alan does too. rofl.

Melody