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03-04-2019, 11:08 PM | #1 | ||
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Junior Member
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"Are you going to give it a try?seems to be a harmless drug other than stomach discomfort"
I thought a bit about it, but I've heard that oral administration has proved an ineffective route. The focus of the trials is on topical administration because of this and because of safety issues. Of course, it's early very, very early days. I also worry about potential side-effects (I actually have colitis, but have also heard of possible concerns regarding dementia, though haven't read anything to this fact). I believe that research will be coming out in a few months regarding early trials of the topical lotion. It's a long-shot. But at least it is something. Cheers Paul |
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"Thanks for this!" says: | Lerch (05-27-2019) |
03-05-2019, 06:52 AM | #2 | ||
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Quote:
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03-05-2019, 10:25 AM | #3 | ||
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03-05-2019, 11:38 PM | #4 | ||
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Junior Member
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Quote:
Just click on ''download PDF'' and you'll be able to see it. If you do a key word search on oral within the pdf,you'll be able to see that it is effective US2�19��4654�A1 - Treatments for diabetic symmetrical polyneuropathy - Google Patents Also i spoke to someone on reddit which stated that they were working on a topical drug for neuropathy which is going really well,didn't state which company or cream ,but pretty obvious :P We are two scientists and we are walking into a bar AMA! : IAmA Last edited by liquidz1; 03-06-2019 at 12:21 AM. |
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"Thanks for this!" says: | northerngal (08-19-2019) |
03-06-2019, 01:00 PM | #5 | ||
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Junior Member
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Two very encouraging quotes from "We are two scientists and we are walking into a bar AMA! : IAmA" link above
"I'm currently working on a topical drug specifically targeting small fiber neuropathy. We are in phase II clinical trials and it's going really, really well. It's a topical drug that should really help with basically no side effects" "We think our cure works regardless of the etiology behind the neuropathy, but there are some exceptions to this rule" |
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"Thanks for this!" says: | northerngal (08-19-2019), Streetlegal (04-11-2019) |
03-06-2019, 01:35 PM | #6 | ||
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Quote:
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01-29-2021, 03:06 PM | #7 | ||
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Junior Member
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Does anyone know of a legal source for purchasing medical grade pirenzepine to be compounded into a topical medication? So far, I have discovered it is not available in the u.s. and I think Mexico. You can get 25 mg tablets from Japan but not sure of the quality or purity. I do not want to break a law, just that at age 73, and considering reports of safety that I have nothing to lose. thanks and best to all
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05-12-2021, 09:08 AM | #8 | ||
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Junior Member
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are there any avenues for "compassionate use" available during trials as I understand that this therapy will not apply to those whose nerves are destroyed meaning you must have some residual nerves available. for long haulers, or those who are becoming long haulers post diagnosis, by the time pirenzepine is available, it will be too late.
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05-14-2021, 09:40 PM | #9 | ||
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Junior Member
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For anyone who might want them, I have a whole load of Oxytrol boxes, unopened if anyone in the San Francisco area wants to take them off my hands for free. I stopped the treatment over a year ago and went back on nortripyline.
Oxytrol contains pirenzipine. |
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11-02-2021, 06:38 AM | #10 | ||
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Hi, I would be interested in this information also.
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