Welcome UKGuy,



It is one of the possible tools in the toolkit against PN. I have taken it a couple of years back because I got reduced effect from the tramadol I was taking. So I tapered that down and started taking Ami. It does work, oddly enough, but the side effects were horrible to me, so after a few weeks I started tapering off again and went back to tramadol.

Some of the meds that are used with PN are antidepressants and/or anti-seizure meds of some sort. Lyrica* is now first choice for diabetic PN, but it's primary role is supposed to be an anti-seizure. Note that I tried that too, but it had nowhere near the effect amitriptyline had on me, and that is about 100 times cheaper.


* back in 2010, the neurologist who put me on Lyrica had to declare in writing that I also had a depression, and had tried all other meds, otherwise he could not prescribe it to me - no doubt a local quirk.