Reply
 
Thread Tools Display Modes
Old 07-09-2019, 05:59 AM #1
Dargx Dargx is offline
Junior Member
 
Join Date: Apr 2019
Posts: 12
Dargx Dargx is offline
Junior Member
 
Join Date: Apr 2019
Posts: 12
Default Questions about B12 intake (and withdrawal)

Hello.

For my PNP I've been taking 5000 micrograms/day of methylcobalamine (and folic acid plus r-lipoic) during 40 days or so and until a month ago when a doctor suggested to stop it due to high values of B12 showed in serum.

The highs in that analytic were:

B12: >1500 pg/mL
Folic acid: > 24.10 ng/mL
Serum urea: 52 mg/dL
Creatinine: 1.15 mg/dL
Uric acid: 7.02 mg/dL
Cholesterol: 289 mg/dL (btw I'm in strict AIP diet and 1st time in 47 years with high cholesterol)
IgA: 409 mg/dL

Now, ten days ago I feel much worse. In fact worse than before supplementation. More paresthesia in hands, burning, electric pain, and so on. Since the PNP started 7 months ago, my hands were almost without sympthoms. Now are much worse than my feet. The odd is that two weeks ago I was really well. In fact I thought I was almost cured.

So the question is: Was a wise decision to stop taking B12 and Folic acid as my doctor suggested? He also said that B12 levels would take months to be at normal levels despite of stopping the intake.

Could be possible the worsening has been due to sudden withdrawal (from 5000 to 0) ?

Is it safe to keep those so high B12 levels?

I wonder if I should start again the intake asap or wait for a new blood analytic ...

Thanks in advance.


Regards.
Dargx is offline   Reply With QuoteReply With Quote
Old 07-09-2019, 08:23 AM #2
glenntaj glenntaj is offline
Magnate
Community Welcome Team
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,778
10 yr Member
glenntaj glenntaj is offline
Magnate
Community Welcome Team
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,778
My Mood: Questions about B12 intake (and withdrawal)
10 yr Member
Default I wouldn't be that worried about--

--that B12 serum level given the amount of cobalamin you've been supplementing with. And that folic acid level is barely above the range of most labs, and not above the range for some (have you also been supplementing with any other B-complex?)

If you feel your symptoms are worsening without supplement, you can play with dosage. You can try 1000mcg/day of methylcobalamin and see where that leaves you in a couple of months.

As far as I have been able to research, there is no known toxicity level for B12--there have been studies in which supplementation went as high as 36000mcg/day with no apparent deleterious effects besides very golden urine--but being above the range like that will make less informed physicians nervous. But you have been supplementing aggressively, so it would be more worrisome if your levels WEREN'T high as a result. (I constantly explain my high B12 levels to new physicians by telling them about my supplement regimen.)
glenntaj is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
echoes long ago (07-09-2019)
Old 07-09-2019, 10:53 AM #3
Dargx Dargx is offline
Junior Member
 
Join Date: Apr 2019
Posts: 12
Dargx Dargx is offline
Junior Member
 
Join Date: Apr 2019
Posts: 12
Default

Thanks a lot for your comment Glenn.

I decided to take 5k/day of B12 based on this this page from a MrsD's post:

~~SUPPLEMENTS~~~ for Peripheral Neuropathy:

I don't know if that information is still valid or is outdated.

Instead of 1k/day, is ok to take 5k every TWO days? Just to finish the cannister


Regards.
Dargx is offline   Reply With QuoteReply With Quote
Old 07-10-2019, 07:00 AM #4
glenntaj glenntaj is offline
Magnate
Community Welcome Team
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,778
10 yr Member
glenntaj glenntaj is offline
Magnate
Community Welcome Team
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,778
My Mood: Questions about B12 intake (and withdrawal)
10 yr Member
Default Don't think there'd be any problem with that--

--or you could try it every three days, or you could even split the pills in half, if that's feasible.
glenntaj is offline   Reply With QuoteReply With Quote
Reply

Tags
acid, ago, b12, intake, mg/dl

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
Lyrica withdrawal questions Woogs Medications & Treatments 1 12-04-2015 07:43 PM
Iron intake and the risk of PD lab rat Parkinson's Disease 0 09-04-2015 04:48 AM
New Member with questions about Lyrica withdrawal thebrunz New Member Introductions 2 11-19-2014 09:55 AM
FYI:calcium intake bizi Weight Loss & Healthy Living 5 03-14-2011 03:36 PM
My intake response befuddled2 Bipolar Disorder 1 07-10-2009 03:59 AM


All times are GMT -5. The time now is 08:57 AM.

Powered by vBulletin • Copyright ©2000 - 2019, Jelsoft Enterprises Ltd.
Search Engine Optimisation provided by DragonByte SEO v2.0.31 (Lite) - vBulletin Mods & Addons Copyright © 2019 DragonByte Technologies Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2019 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.