it says in that report
alpha lipoic acid, offers little benefit

That's not what I see in the report, gert?

The quote I posted is from the link kiwi provided you. Diabetic neuropathic pain: Physiopathology and treatment

The R vs S (synthetic) - Synthetic type may be less benefit.. so best to get non S..
Info--
R-Form Alpha-Lipoic Acid vs. S-Form Alpha-Lipoic Acid | ConsumerLab.com

There are other antioxidant and anti-inflammatory supplements that may be beneficial.
antioxidant and anti-inflammatory supplements at DuckDuckGo

A good resource for checking brand ratings..
ConsumerLab.com - independent tests and reviews of vitamin, mineral, and herbal supplements | Consumerlab.com

Adding to what Jo*mar wrote, this thread discusses the differences between S-lipoic acid and R-lipoic acid.

Which kind of Lipoic Acid?

Here is what the Linus Pauling institute says about Lipoic Acid


Please google "linus pauling institute lipoic acid" as I am not allowed to post links being a newbie

**


What is really confusing is there is no clear consensus on which form (R or the racemic RS form is better). **

Admin Note: Sorry but this post has also been edited as we are not allowed to have copy/paste from websites that have Copyright. Only the link to the article is allowed when the poster has reached linking default membership

ok it says that the studies on the benefits of Alpha-linolenic acid are sponsored by the manufacturer of the Alpha-linolenic acid.

Thanks..

Last year my bloodwork showed elevated sugar, but no formal diabetes diagnosis ..

This year when PN flared up about a month ago, I was on a low carb diet trying to loose weight.. (I am about 40lbs overweight)..

When the doctor ordered bloodwork , everything came back fine. My question is:

Is it possible that , my elevated sugars already did the damage to my nerves, by the time I switched over to a low carb diet , so that the bloodwork could not detect any diabetes/prediabetes ?

I have a doctors appointment this week, and I am trying to formulate the right questions to ask, as some of the primary care doctors are quite dismissive about neuropathy

A couple comments on this thread:
-Metanx is a prescription "medical food" that is intended to treat peripheral neuropathy. the active ingredients are L-methylfolate, methylcobalamin and pyridoxal 5-phosphate. Obviously, you can buy each of these over the counter if you wanted to. I have taken all those supplements in combination and it does seem to help. Later I stopped taking the high doses of P-5-P because other studies indicate it can actually cause PN for some people. Unfortunately, nothing works for everyone and for some people nothing seems to work. You just have to research and try things to try and hit on the combination that works best for you.

-There is some research that seems to indicate that it is possible for nerve damage to be done while people are still in the pre-diabetic phase. But just like much of the information related to PN, there is no definitive proof of this.

Folks anyone with high uric acid and peripheral neuropathy?. I have high uric acid and prescribed 200mg allopurinol for that .. Currently the allopurinol is on hold to see if that is related to my PN.

I tested my Serum UA today and found it to be 7.8 mg/DL (should be 7.2 or below).


I found the link below which describes a possible link between Serum UA and PN

google "can high uric acid cause neuropathy?" and see the results as I cannot post links