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Gosh, I see why you would get confused. I will, for myself, try to write more clearly from now on. When I say that someone should get Methylcobalamin and only Methylcobalamin, I mean that they should not get the cyanocobalamin form... which works if someone is not very deficient, but isn't as effective if someone needs a lot of repair. And yes, you should take a B complex with it.. B vitamins work best as a group. It's good to remember that Folic acid can mask the signs of low B12... this last summer I was taking a lot of B Complex to rid me of my allergies, which it does, and very well, I might add. But then I wasn't having many syptoms of low B12, so I began to have less B12 injections. Everything was fine for a short time, then not so fine. So I now realize that if I take a lot of the B vitamins it seems to relieve symptoms of low B12... and I suppose in fact it relieves those symptoms because they are also symptoms of low B vitamins of other kinds, as well. So yes, do take the Methylcobalamin and a B complex to go with it. As an aside, there's an internet vitamin company that does ship to Mexico: Vitacost. I order from them every month, and have been very satisfied. You should be able to google them. :) :) **** Oh Gosh, re the hyperbaric... I looked into it when I had the hydrogen sulfide poisoning ... and I found one really interesting article about some team, I forget if it was NFL or baseball, but they got a chamber for injured players, but then all the players started using it and then they stopped EVER winning home games. The author of the article was attached to the team in some way, but I forget how. He guessed that the reason they stopped winning home games was the hyperbaric chamber... apparently it depletes negative ions... He guessed that the reason they won away games was that they were able to get more negative ions into their systems... So then I read about negative ions and they come from the sea air, pine forest air... and Epsom salts baths' steam... At the time I was on Celebrex to reduce the swelling around my sternum that was causing a lot of chest pain... but I would still get major swelling in my ankles, and the Epsom salts helped a lot. I have a neat page on Epsom salts... Maybe if you Google it will come up for you. :) |
Cyanocobalamin is not just for people who aren't very deficient. If that is the form someone can get, and they are very deficient and even malbsorb B12 severely, it is almost a sure thing that they will be able to convert to methylcobalamin and repair what is repairable.
However, more methylcobalamin is an extra edge that is very important to a small minority of those who need B12. It's like buying a rider on your insurance policy. And since the price is not high, if you can get it, why not? Please, those who can only get cyanocobalamin, do not believe that cyanocobalamin is not for people with serious problems, even near death due to B12 deficiency. It has been saving lives for over half a century! Only if you are in a small minority will it not give you what you need. rose |
What causes me to say that anyone who needs replacement a lot, should get the Methylcobalamin, is that before I understood about B12, but I had seen my test results and where the doctor had written that I had a PROFOUND B12 deficiency, I went to the store and got a MegaB complex with B12 in it in the cyanocobalamin form.
I took a lot of them, with a lot of liquid, all day long. And they got rid of my allergies, completely! So that was dynamite. But when I had a B12 test there was NO difference in my level. NONE. Some time after that I worked with a young girl who had quite a lot of stress and she was so exhausted all the time. She was beautiful, everyone agreed about that, but she was just so so so tired. When I saw that she had ridges on her fingernails I got her to buy a B vitamin complex, and for her it worked great. She began to feel so much different, and she went to college and was so different. She came back to tell me about all the changes in her life. So, from those experiences I have to admit that the cyanocobalamin form works for some people. However, I KNOW that it did not work for me because I had B12 tests before and after taking several bottles of it. Everyone should keep notes so they can see how things work for them... For sure! Most healthfood stores carry Methylcobalamin. And in countries where their healthfood stores don't carry it, there are vitamin places that ship to many of those countries. :) Rose wrote. Quote:
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Keeping it simple....
B-6 one can get toxic effects from...just web up 'B-6-Toxicity'.
B-12 it's really really hard to get toxic effects from. Web it up...should be hard to find. That there are different forms of B-12, as all say, is what you can get is part of the issue. Most B-12 overdoses are like trying to OD on Vitamin C...it just passes thru you. But, making sure what all B-12 that's swimming around in your blood and actually being asorbed and used...well that is a different issue. Blood tests really don't tell docs what's BEING USED, just what's out there in your blood to BE used. Big difference. Only way to be sure are thru biopsies and since we are 'susceptable' to begin with...this isn't a way to go. Not worth it, and the tests to date are filled with room for error. SOO, If asorbtion is an issue [as is possibly my own case] taking the Methyl...and well, doing what atheletes do to hydrate before running races [overload or 'pack' the stuff] increases your chances of 'taking up' what you need. Since taking too much usually is very hard to hurt you, it should be worth trying for, say about 3-6 months? and see if anything [maybe slowly] makes a difference? B-6 on the other hand can cause problems....I know it's confusing, I've been working on it for the 3 years I've been on this and other boards and I'm still confused. It's the get too much info and the brain circuits fry - syndrome! Don't know how else to put it. YOu are on the right track, learning asking questions - but it's YOU who has to decide what is good for YOU! No one else can do that! :hug: :hug: 's - j |
Brian, I have bought Methyl B12 from Mr Vitamins in Chatswood. http://www.mrvitamins.com.au. It is classified as 'Practitioner only' and is kept behind a counter. Manufacturer is Thorne (USA) and it is only available in 1000 microgram capsules. It is quite expensive. No idea of the quality.
I ordered methyl B12 from Iherb about a year ago but never received the goods - I assume they were confiscated by Aus customs. I am interested to hear more about people who have successfully purchased from Iherb as methyl B12 is much cheaper (per microgram) from them even with the delivery costs. Martin |
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Wow, you were paying $70 a bottle for Methylcobalamin? How big was the bottle... ???? :) I just checked the coutries page on my web site and saw that it is shipped from Vitacost to Australia. Vitacost is a discount vitamins company. I order from them all the time. But in terms of shots, I have to agree with you, the shots work really well and are vastly cheaper. The main reason I don't talk more about getting the shots is that you have to have a doctor's prescription, and some doctors just do not get it. (and therefore withhold prescriptions for B12) It was by luck that I went to a holistic M.D. just before I got tetanus and she gave me a prescription for a shot a day for a year. :) A shot a day for a month is about $6 from Wal*Mart here, so it's CHEAP. I can afford it. I love it. But if someone wants to know if it will help them, they can buy a bottle of the Methylcobalamin lozenges that will last a couple months, I get the 5mg ones for when I just cannot stand another shot... because of the needle... and a bottle of those is around $16. (I also send them to old friends... people who I don't think would find out about it in normal daily life... but who might have a heart health need for it.) :) |
Everyone cannot get methylcobalamin.
As I have said before, Karen's experience is unusual. And if anyone has a choice between cyanocobalamin and methylcobalamin, I think they would be foolish not to choose methylcobalamin. However, most people can use cyanocobalamin. And, if Karen had a response to the cyanocobalamin, as she posted, it was getting through and doing her good. The test results are not reliable, and they can fail to move up for quite a while, until stores begin to be filled. She may have been far more deficient than the initial test result showed. There is no way to know whether those of us who switched to methylcobalamin have had better repairs because of that than if we had continued with cyanocobalamin. Scientific evidence useful to most people is not derived from the very few exceptions. As I said before, methylcobalamin covers some less likely possibilities. Cyanocobalamin can do the job for most, if they get enough often enough. Better would be hydoxocobalamin, and best methylcobalamin. rose |
Thorne should be very good quality, but oh that price!
rose |
B12 that is in the blood has been absorbed, but there is no guarantee that it will be stored or used.
In almost all cases though, as the B12 result increases with treatment, and eventually gets very strong (around 1000 or more) it becomes very clear that stores are being filled, or have been filled. It is very unusual for someone to fail to build stores and use B12 well when taking 1000 - 2000 mcg cyanocobalamin per day, and it is even more unusual when taking methylcobalamin. Very rare. Methylcobalamin has been proven safe in extremely large quantities, even regular doses in people who cannot remove it normally because of kidney disease. rose |
The B12 research is interesting. If you read it you will see that in each study there are people who have more or less response to B12. In many studies the amount of response is correlated with the length of time the person has been deficient. I have a lot of research excerpts on my site. They are very interesting.
I had a positive response immediately from the B12 injections, but I was given few and had to beg for more once my B12 level went up a little bit. B12 tests are mostly done on the B12 in blood... so replacement therapy affects that quite a lot. The methylmalonic acid tests are apparently quite different in results if they are done on spinal fluid... which indicates a much "deeper" kind of depletion... For me, when I took a lot of cyanocobalamin in tablet form, it made NO difference to my test results. I was having regular B12 tests at the time, so I was able to see that. It is really REALLY important to take notes when you take B12 so that you can go back and see what it did for you... else you may be "thinking" it did or didn't do something, and your memory may not be entirely accurate. I'm saying that because my memory was affected by my low levels of B12, so I'm really glad my neurologist said to keep a Time Line. :) Rose wrote- Quote:
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