Hello, I was wondering on a dosage with r lipoic acid, I have been taking 100 mg a day for my P/N but have been reading online a lot of sites suggest 600mg a day. Do you think that is too much a day?

I take a single capsule of 600mg of Alpha Lipoic Acid for PN daily. I don't know if your stuff is the same thing or a variant. There's so much clever marketing for active ingredients etc, its difficult to tell.

Hope this helps.

--is the active right sided molecular isomer isolated from the various types in alpha lipoic acid; for some reason, the left-sided isomer seems to be inactive in humans.

Part of the reason r lipoic acid was developed was that discovery and the fact that many people taking alpha lipoic acid did experience some acidic stomach/reflux side effects; it was thought that isolating the active isomer would enable people to take lower, less acidic doses for a similar effect.

I've seen people claim that ration of 6:1 alpha vs. r for a similar effect--e.g., that taking 100mg of r produces a similar benefit as 600mg of alpha--but I suspect the ration is rather individual and one might need to experiment somewhat to find out.

Hi Thank you for the reply, I will read what is on the bottle: Jarrow formulas R-ALpha Lipoic Acid plus Biotin 100 Mg Stabilized 60 veggie caps Superior bioavailability and activity, not sure on right sided or left sided isomer. I take one 100 mg cap each morning. A lot say to take acetyl-l- carnitine and benfotiamine along with it but I am not sure what that combo would do to benefit the r lipoic acids effectiveness.

Hi, I forgot to mention on the R alfa lipoic acid I have, it also says on the bottle: Na Rala not sure what this is,

--is just the chemical symbol for sodium; the R-lipoic Acid is complexed in a sodium molecule.

Hi and thanks for all who replied, I should I guess be ok with the ones I have at 100mg a day, i just did not want to under dose and not get the full effectiveness of the supplement and stop using them down the road thinking it is not working for me. I guess its hit and miss as everyone is different. Experimental some what, up the dose down the dose till you either feel some relief from it or not. How about the acetyl-l-carnitine and the befotiamine for SFN, has anyone had any good progress by using these two with R alfa lipoic acid?

Ive been taking 2 300mg alpha lipoic acid caps for about three months. my endocrinologist told me just this week it may take a year for results. my pn is getting a little worse but the Alpha lipoic acid could be helping.... grabbing at any straws here...