What is small fibers neuropathy?

small fiber peripheral neuropathy involves the small nerve fibers that usually do not have a myelin sheath. Small nerve fibers in the skin subsume the sensations of touch and temperature. Damage to the small nerve fibers will not show up on an EMG/NCS Electromyography/ Nerve conduction study.


Your symptoms sound like small fiber peripheral neuropathy. A skin punch biopsy will show the amount of small fiber nerve damage you have and is used for a diagnosis. I have had it done. it was not painful and no complications afterwards at all.

You really think my symptoms sound like this condition I totally thought it was allodynia because of my clothing issue with the fabrics. Who could I ask to do a small skin biopsy? Could I ask my dermatologist to do it?

So, my skin sensitvity to the textures of clothes as well as the fittedness of clothes and my legs going numb and having a tingling feeling after sitting for a while. All of this could be small fiber neuropathy? Can I ask what you're symptoms were and did you end up getting diagnosed with it? Also, who did your skin biopsy, was it a dermatologist?