Hey Damlays,

It took roughly 4.5 to 5 months initially for me to return to normal the first time. I cannot be as specific the second time because I have adopted the attitude of just getting on with life and making the best of things. I was able to drink small amounts on several occasions, I suppose I became over confident. If I had to say a timescale maybe 3 months. It's strange that the symptoms become worse after cessation before they become better. I'm not sure I've ever been completely symptom free. If I become aware of my body thing is tingling here and there. But I choose, as I say, to ignore it.

What is Nucleo C.M.P Forte? It's not available in the UK. Do you have it on prescription? Where do you get it and what does it do?

Are you taking Vitamin B12 in addition to multi B ? In addition I would consider Benfotiamine the fat soluble version of B1. It means we can store it in our livers rather than have it pass through our body in our urine. Something else I would consider is Magnesium Threonate. Magnesium is great for nerve healing and symptom relief.

I find it extraordinary that a carb meal can cause you such pain. I am struggling to get my head round the mechanism for that. I am aware that high glucose levels in the blood are toxic for nerves. This is the basis of diabetic neuropathy. Carbs break down into glucose that can damage the small blood vessels that supply the nerves causing nerve damage and neuropathic symptoms. But this is a slow process. I have read that high glucose levels cause the nerves to swell cutting off blood supply to the nerves and pain however not from a reputable source.

Oxidative stress takes us to the world of free radicals and anti oxidants. I can't imagine that this would be the cause of your post meal pain as oxidative stress takes place with all kinds of foods and activities. Have you had this diagnosed or have you arrived at this conclusion yourself? If you have further reading links I would love to see.

Anti oxidants as I'm sure you know are essential to a healthy diet. The foods with the highest concentrations of anti oxidants are Amla. Are you familiar with this? I have this in powdered form and also Triphala Powder. I add it to my porridge and soups. Please note it is an acquired taste! Disguise it with something nice! A wide range of fruit and vegetables, especially green leafy and cruciferous vegetables and dark berries are also essentials. Green Tea and Hibiscus tea are also loaded with anti oxidants.

I hope you're making progress and I hope this helps. Please let me know your thoughts and about the Nucleo C.M.P Forte.

Best wishes,

Atty

(At first time I wrote this reply I shared with you many links but this website didn't allow me to post links because my posts were not enough. So I deleted all and wrote LiNK LiNK in their place. Maybe later I can post or find another way to share.. Now I can only post my text without my links.)


Hi Atticus,


It is a combination with
Cytidine-5′-disodium monophosphate &
Uridine-5′-trisodium triphosphate

It is an external source of pyrimidine nucleotides (PN) necessary for reparation of a nerve tissue, is widely used in the treatment of peripheral neuropathy.


LiNK LiNK LiNK LiNK 1



I am originally from Europe, but currently living in South East Asia as an expat because of my business. In the pharmacies it is very easy to find here w/o Rx.

Yes I am taking both B12 and Benfotiamine. As I know because of Benfotiamine is fat soluble bioavailability is much more better than B1. But I didn't read anything about it is stored in liver. I will be glad if you share a link about that.

I am using ordinary Magnesium support instead of Magnesium Threonate. As I know the only advantage of Magnesium Threonate is easy passing Blood Brain Barrier (BBB), so it is good for treatment of Central Nervous System issues. But my case is about sensory and autonomic peripheral nervous system, I didn't think I need this advantange. Am I wrong?

Yes it is very interesting that this subject didn't enter to the medical books as a well-known fact. When I said to Neurology Specialists they could not find a firm and exact explanation about it also.

But this is a FACT.. and when I search deeper I saw one by one individual events and medical articles which can be combined together and turned into a meaningful picture, additionally I found some other people who are exactly facing with the same situation like me.

First of all this is not about high blood glucose. For explaining this fact the main KEYWORD is "Neuroinflammation" which describes a micro inflammation of neurons in cellular level that disturbs neurons itself and their myelins.

2 years ago I read many medical articles and patient experiences about it (I saved my links but I cannot find right now, if I find I can share deeper info). This can be about 2 factors (one of them or both together)
- The things we eat increases neuroinflammation
- The things we eat increases Insulin, high insulin itself is another factor which directly disturbs the neurons

When I read more I discovered that I am not alone in this thing. Some other people also have exactly same issue with me, and they have to avoid from some type of foods because those food increase their symptoms just 10-15 minutes after eating.

For example I found this page, patients are telling exactly same situation which I had and explaining the reason as well

LiNK LiNK LiNK LiNK 2

And there is a very well known thing which you can find a lot of information on the net about it: Ketogenic Diet (or Keto-Diet)


Keto-diet is done exactly for this purpose, for decreasing the cellular base inflammation, because especially glucose and some others are increasing this inflammation (and neuroinflammation as well)

So how I protected myself from symptoms and healed myself, the MAIN answer for this is: "I always continued an Anti-Inflammatory Ketogenic Eating".

PS.
I couldn't find my main links yet but just by searching now I found some -Partially- related articles

LiNK LiNK LiNK LiNK 3

Because of my keto-diet I cannot eat many fruits also because fructose is definitively number one cause which is immediately increasing my symptoms.

I made anti-oxidant therapy by taking ALA, NAC, Omega III and Rutin.

You asked the effect of Nucleo C.M.P Forte. Actually I am taking all these pills but I cannot measure their direct effect coming of them immediately, so it is very hard to say which one is working which one is not working, or which one is how much working. I am blind about that, the only thing I can depend is the medical articles which I read.

But only about one thing I can observe directly and be sure is Ketogenic diet makes me better (related with that 2 reasons I wrote above) and whenever I damage my strict keto-diet my symptoms highly exacerbate immediately.

Thank you very much. I still cannot believe after very difficultly recovery in 2 years, how I immediately turned back exactly to the beginning just in 1 day with only 2 beers. The people who is reading this post should take this lesson and NEVER EVER try alcohol again in their life after recovery!

Hey Damlays,

Thanks for your reply. First of all I want to say that it really is terrible that such a simple pleasure as a couple of beers could result in such awful symptoms. It really is, on several levels, an awful experience and having lived it, in some sense myself, I sympathize with you.

Thanks for the information about C.M.P Forte.

Yes I am taking both B12 and Benfotiamine. As I know because of Benfotiamine is fat soluble bioavailability is much more better than B1. But I didn't read anything about it is stored in liver. I will be glad if you share a link about that.

I can't find any links that say that. I have got it wrong. However I'm sure I read it somewhere. Maybe I assumed because it was fat soluble it could be stored. My mistake, sorry. Nevertheless, it is the superior form of Thiamine in terms of bioavailability and I'm glad you're taking it.

I am using ordinary Magnesium support instead of Magnesium Threonate. As I know the only advantage of Magnesium Threonate is easy passing Blood Brain Barrier (BBB), so it is good for treatment of Central Nervous System issues. But my case is about sensory and autonomic peripheral nervous system, I didn't think I need this advantange. Am I wrong?


No I don't think you're wrong. However I'm not sure its a good idea to separate the CNS and the PNS and Threonate as you say crosses the BBB. If it also protects my CNS then all the better. I also believe Threonate is the best form because of it's superior bioavailability and also its a molecule that helps with sleep.

I am very much interested in seeing your links. Once you have reached 10 posts you can do this. I am very much interested in the role of oxidative stress in your PN also the influence of diet.

Have you looked at Berberine. I discovered it from the "longevity community." I take it before meals. It has an action similar to metformin the diabetic medication. I wonder if it would help you and help alleviate post meal symptoms.

Berberine: A Powerful Supplement With Many Benefits

http://research.shahed.ac.ir/WSR/Sit...1093616358.pdf

This is another paper I think you'd be interested in. The role of dietary nutrients in PN Regeneration. It talks about ketogenic diets amongst other things.

The Role of Dietary Nutrients in Peripheral Nerve Regeneration

Hoping you're seeing some improvements,

Best wishes,

Atty

Thank you.. I will check the links you sent.

And I will post again here my links when I become able to post links.

Hope to see you again.

How is your progress? Did you recover a little bit at least? I myself plan to drink a cup of wine on my next birthday as my doctor told me I would be able to drink a little bit occasionally, but am too scared to ruin all the work I have done.

jean2399, a number of people I've known have been helped by Alcoholics Anonymous, which might be available where you are. Some people dislike AA's approach but many find it useful.

AA's position has always been that alcohol is like a poison to an alcoholic, and the recovering alcoholic should just learn to avoid any drinking.

Alcohol Abstinence: Can I Be in AA and Still Drink?

I would find a new Doctor. That is horrible advice. Go with your gut on this one.

Thanks. Don't worry! I don't think I will see this doctor too often. This is public health here, so I don't have much choice, but to see a private one. I don't think I will fall for drinking again. I don't want to go through this **** again.